Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Kcnc3provided by MGI
Official Full Name: potassium voltage gated channel, Shaw-related subfamily, member 3provided by MGI
Primary source: MGI:MGI:96669
See related: Ensembl:ENSMUSG00000062785 AllianceGenome:MGI:96669
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Kv3.3; Kcr2-3; KShIIID
Summary: Predicted to enable delayed rectifier potassium channel activity. Acts upstream of or within regulation of neurotransmitter secretion. Located in several cellular components, including neuromuscular junction; neuron projection membrane; and neuronal cell body membrane. Is expressed in aortic valve; arch of aorta; brain; descending thoracic aorta; and thoracic aorta. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 13. Orthologous to human KCNC3 (potassium voltage-gated channel subfamily C member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in cerebellum adult (RPKM 72.8), lung adult (RPKM 11.9) and 6 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 B3; 7 28.85 cM

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (44236405..44254175)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (44586939..44604751)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A missense mutation in Kcnc3 causes hippocampal learning deficits in mice.
Title: A missense mutation in Kcnc3 causes hippocampal learning deficits in mice.
Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1.
Title: Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1.
Kv3 transcripts and proteins show a progressive increase in expression and reached an asymptote in adulthood, suggesting that the increase in Kv3 expression during development might contribute to the maturation of the electrical activity of neurons.
Title: Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease.
Dendritic Kv3.3 potassium channels in mice cerebellar purkinje cells regulate generation and spatial dynamics of dendritic Ca2+ spikes.
Title: Dendritic Kv3.3 potassium channels in cerebellar purkinje cells regulate generation and spatial dynamics of dendritic Ca2+ spikes.
Kv3.3 expression in Purkinje cells is necessary for normal motor speed but not gait pattern.
Title: Rescue of motor coordination by Purkinje cell-targeted restoration of Kv3.3 channels in Kcnc3-null mice requires Kcnc1.
Kv3.3 potassium subunits are expressed in both GAD- and GAD+ cells, albeit at different densities and distribution. They likely contribute to the distinct biophysical properties of both GAD- and GAD+ neurons in the dentate nucleus.
Title: Subcellular localization of the voltage-gated potassium channels Kv3.1b and Kv3.3 in the cerebellar dentate nucleus of glutamic acid decarboxylase 67-green fluorescent protein transgenic mice.
results support the hypothesis that altered electrophysiological properties of TRN neurons contribute to the reduced EEG power at slow frequencies in the thalamocortical network of Kv3-deficient mice.
Title: Ablation of Kv3.1 and Kv3.3 potassium channels disrupts thalamocortical oscillations in vitro and in vivo.
Purkinje-cell-restricted restoration of Kv3.3 function restores complex spikes and rescues motor coordination in Kcnc3 mutants.
Title: Purkinje-cell-restricted restoration of Kv3.3 function restores complex spikes and rescues motor coordination in Kcnc3 mutants.
Kv3.3 channels are required for generation of the repetitive spikelets of the complex spike.
Title: Kv3.3 channels at the Purkinje cell soma are necessary for generation of the classical complex spike waveform.
In this study, we identified additional populations and subcellular compartments that are likely to sustain high-frequency firing because of the expression of Kv3.3 and other Kv3 subunits.
Title: Distribution of Kv3.3 potassium channel subunits in distinct neuronal populations of mouse brain.

Submit: New GeneRIF Correction See all GeneRIFs (14)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1) 1 citation
Chemically induced (ENU) (1) 1 citation
Endonuclease-mediated (4) 1 citation

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables delayed rectifier potassium channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables monoatomic ion channel activity	IEA Inferred from Electronic Annotation more info
enables potassium channel activity	IEA Inferred from Electronic Annotation more info
enables voltage-gated potassium channel activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in action potential	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in potassium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in potassium ion transmembrane transport	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within potassium ion transport	IEA Inferred from Electronic Annotation more info
involved_in potassium ion transport	IEA Inferred from Electronic Annotation more info
involved_in protein homooligomerization	IEA Inferred from Electronic Annotation more info
involved_in protein tetramerization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of neurotransmitter secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of synaptic vesicle endocytosis	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of synaptic vesicle endocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in axolemma	IDA Inferred from Direct Assay more info	PubMed
is_active_in axon terminus	IBA Inferred from Biological aspect of Ancestor more info
located_in axon terminus	IDA Inferred from Direct Assay more info	PubMed
is_active_in calyx of Held	IDA Inferred from Direct Assay more info	PubMed
is_active_in calyx of Held	IMP Inferred from Mutant Phenotype more info	PubMed
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in dendrite membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in dendrite membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of monoatomic ion channel complex	IEA Inferred from Electronic Annotation more info
located_in neuromuscular junction	IDA Inferred from Direct Assay more info	PubMed
is_active_in neuronal cell body membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in neuronal cell body membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
is_active_in postsynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in postsynaptic membrane	ISO Inferred from Sequence Orthology more info
is_active_in presynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in presynaptic membrane	ISO Inferred from Sequence Orthology more info
located_in synapse	IEA Inferred from Electronic Annotation more info
part_of voltage-gated potassium channel complex	IBA Inferred from Biological aspect of Ancestor more info
part_of voltage-gated potassium channel complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: potassium voltage-gated channel subfamily C member 3

Names: voltage-gated potassium channel subunit Kv3.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001290682.2 → NP_001277611.1 potassium voltage-gated channel subfamily C member 3 isoform 2

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (3) summary

PHA03247
Location:638 → 753

PHA03247; large tegument protein UL36; Provisional

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385625.1 → NP_001372554.1 potassium voltage-gated channel subfamily C member 3 isoform 3

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385626.1 → NP_001372555.1 potassium voltage-gated channel subfamily C member 3 isoform 4

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (3) summary

PHA03247
Location:638 → 781

PHA03247; large tegument protein UL36; Provisional

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385627.1 → NP_001372556.1 potassium voltage-gated channel subfamily C member 3 isoform 5

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHT3, E9QKI2

Related

ENSMUSP00000103539.4, ENSMUST00000107906.6

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385628.1 → NP_001372557.1 potassium voltage-gated channel subfamily C member 3 isoform 6

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385629.1 → NP_001372558.1 potassium voltage-gated channel subfamily C member 3 isoform 7

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (3) summary

PRK12323
Location:641 → 759

PRK12323; DNA polymerase III subunit gamma/tau

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385630.1 → NP_001372559.1 potassium voltage-gated channel subfamily C member 3 isoform 7

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (3) summary

PRK12323
Location:641 → 759

PRK12323; DNA polymerase III subunit gamma/tau

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385631.1 → NP_001372560.1 potassium voltage-gated channel subfamily C member 3 isoform 2

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (3) summary

PHA03247
Location:638 → 753

PHA03247; large tegument protein UL36; Provisional

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385632.1 → NP_001372561.1 potassium voltage-gated channel subfamily C member 3 isoform 8

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHI4, A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385633.1 → NP_001372562.1 potassium voltage-gated channel subfamily C member 3 isoform 8

Status: VALIDATED

Source sequence(s)

AC157653

UniProtKB/TrEMBL

A0A140LHI4, A0A140LHT3

Related

ENSMUSP00000146425.2, ENSMUST00000207493.2

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
NM_001385634.1 → NP_001372563.1 potassium voltage-gated channel subfamily C member 3 isoform 9

Status: VALIDATED

Source sequence(s)

AC157653

Conserved Domains (1) summary

pfam00520
Location:1 → 186

Ion_trans; Ion transport protein
NM_001385635.1 → NP_001372564.1 potassium voltage-gated channel subfamily C member 3 isoform 10

Status: VALIDATED

Source sequence(s)

AC157653

Conserved Domains (1) summary

pfam00520
Location:1 → 186

Ion_trans; Ion transport protein
NM_001385636.1 → NP_001372565.1 potassium voltage-gated channel subfamily C member 3 isoform 11

Status: VALIDATED

Source sequence(s)

AC157653

Conserved Domains (1) summary

pfam00520
Location:1 → 186

Ion_trans; Ion transport protein
NM_001385637.1 → NP_001372566.1 potassium voltage-gated channel subfamily C member 3 isoform 12

Status: VALIDATED

Source sequence(s)

AC157653

Conserved Domains (1) summary

pfam00520
Location:1 → 186

Ion_trans; Ion transport protein
NM_008422.3 → NP_032448.2 potassium voltage-gated channel subfamily C member 3 isoform 1

See identical proteins and their annotated locations for NP_032448.2

Status: VALIDATED

Source sequence(s)

AC157653

Consensus CDS

CCDS39942.1

UniProtKB/Swiss-Prot

D3YZV2, E9Q5E5, Q62088, Q63959

UniProtKB/TrEMBL

A0A140LHT3

Related

ENSMUSP00000103540.3, ENSMUST00000107907.10

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein

RNA

NR_169735.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC157653
NR_169736.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC157653
NR_169737.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC157653

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

44236405..44254175

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036152709.1 → XP_036008602.1 potassium voltage-gated channel subfamily C member 3 isoform X12

Conserved Domains (1) summary

pfam00520
Location:47 → 308

Ion_trans; Ion transport protein
XM_036152714.1 → XP_036008607.1 potassium voltage-gated channel subfamily C member 3 isoform X17

Conserved Domains (1) summary

pfam00520
Location:1 → 186

Ion_trans; Ion transport protein
XM_036152715.1 → XP_036008608.1 potassium voltage-gated channel subfamily C member 3 isoform X18

Conserved Domains (1) summary

pfam00520
Location:1 → 186

Ion_trans; Ion transport protein
XM_036152716.1 → XP_036008609.1 potassium voltage-gated channel subfamily C member 3 isoform X19

Conserved Domains (2) summary

PRK12323
Location:276 → 420

PRK12323; DNA polymerase III subunit gamma/tau

pfam00520
Location:1 → 186

Ion_trans; Ion transport protein
XM_036152717.1 → XP_036008610.1 potassium voltage-gated channel subfamily C member 3 isoform X20

Conserved Domains (2) summary

PHA03247
Location:273 → 419

PHA03247; large tegument protein UL36; Provisional

pfam00520
Location:1 → 186

Ion_trans; Ion transport protein
XM_036152707.1 → XP_036008600.1 potassium voltage-gated channel subfamily C member 3 isoform X8

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (3) summary

PHA03247
Location:638 → 753

PHA03247; large tegument protein UL36; Provisional

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_036152706.1 → XP_036008599.1 potassium voltage-gated channel subfamily C member 3 isoform X7

UniProtKB/TrEMBL

A0A140LHT3

Related

ENSMUSP00000146535.2, ENSMUST00000209177.2

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_036152701.1 → XP_036008594.1 potassium voltage-gated channel subfamily C member 3 isoform X1

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_036152703.1 → XP_036008596.1 potassium voltage-gated channel subfamily C member 3 isoform X3

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_006540658.4 → XP_006540721.1 potassium voltage-gated channel subfamily C member 3 isoform X9

See identical proteins and their annotated locations for XP_006540721.1

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_006540654.4 → XP_006540717.1 potassium voltage-gated channel subfamily C member 3 isoform X6

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_036152702.1 → XP_036008595.1 potassium voltage-gated channel subfamily C member 3 isoform X2

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_036152708.1 → XP_036008601.1 potassium voltage-gated channel subfamily C member 3 isoform X10

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_036152704.1 → XP_036008597.1 potassium voltage-gated channel subfamily C member 3 isoform X4

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (3) summary

PRK12323
Location:641 → 785

PRK12323; DNA polymerase III subunit gamma/tau

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_036152705.1 → XP_036008598.1 potassium voltage-gated channel subfamily C member 3 isoform X5

UniProtKB/TrEMBL

A0A140LHT3

Conserved Domains (3) summary

PHA03247
Location:638 → 784

PHA03247; large tegument protein UL36; Provisional

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_006540661.5 → XP_006540724.1 potassium voltage-gated channel subfamily C member 3 isoform X11

UniProtKB/TrEMBL

A0A140LHT3, A0A140LIW8

Related

ENSMUSP00000146988.2, ENSMUST00000208651.2

Conserved Domains (2) summary

cd18414
Location:91 → 204

BTB_KCNC1_3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily C members KCNC1 and KCNC3

pfam00520
Location:290 → 551

Ion_trans; Ion transport protein
XM_036152712.1 → XP_036008605.1 potassium voltage-gated channel subfamily C member 3 isoform X15

Conserved Domains (1) summary

pfam00520
Location:47 → 308

Ion_trans; Ion transport protein
XM_036152713.1 → XP_036008606.1 potassium voltage-gated channel subfamily C member 3 isoform X16

Conserved Domains (2) summary

PRK12323
Location:398 → 516

PRK12323; DNA polymerase III subunit gamma/tau

pfam00520
Location:47 → 308

Ion_trans; Ion transport protein
XM_036152710.1 → XP_036008603.1 potassium voltage-gated channel subfamily C member 3 isoform X13

Conserved Domains (2) summary

PRK12323
Location:398 → 542

PRK12323; DNA polymerase III subunit gamma/tau

pfam00520
Location:47 → 308

Ion_trans; Ion transport protein
XM_036152711.1 → XP_036008604.1 potassium voltage-gated channel subfamily C member 3 isoform X14

Conserved Domains (2) summary

PHA03247
Location:395 → 541

PHA03247; large tegument protein UL36; Provisional

pfam00520
Location:47 → 308

Ion_trans; Ion transport protein