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    Krt84 keratin 84 [ Mus musculus (house mouse) ]

    Gene ID: 16680, updated on 23-Jun-2021

    Summary

    Official Symbol
    Krt84provided by MGI
    Official Full Name
    keratin 84provided by MGI
    Primary source
    MGI:MGI:96700
    See related
    Ensembl:ENSMUSG00000044294
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HRb-; HRb-1; Krt2-; Krt2-1; Krt2-3; Krt2-16; AV235125
    Expression
    Low expression observed in reference dataset See more
    Orthologs
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    Genomic context

    See Krt84 in Genome Data Viewer
    Location:
    15 F2; 15 56.9 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (101433461..101441255, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (101525026..101532820, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (101355457..101363251, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene type II keratin Kb32P Neighboring gene uncharacterized LOC118568225 Neighboring gene keratin 85 Neighboring gene keratin 82 Neighboring gene keratin 90

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC140837

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of skin epidermis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of keratinocyte differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intermediate filament cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in keratin filament ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    keratin, type II cuticular Hb4
    Names
    65 kDa type II keratin
    K84
    keratin complex 2, basic, gene 16
    keratin complex 2, gene 16
    type II hair keratin Hb4
    type-II keratin Kb24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008474.2NP_032500.2  keratin, type II cuticular Hb4

      See identical proteins and their annotated locations for NP_032500.2

      Status: VALIDATED

      Source sequence(s)
      AA738772, BC114971, BY779643, CF173770, CJ052880
      Consensus CDS
      CCDS27853.1
      UniProtKB/Swiss-Prot
      Q99M73
      Related
      ENSMUSP00000023720.8, ENSMUST00000023720.8
      Conserved Domains (4) summary
      pfam00038
      Location:173483
      Filament; Intermediate filament protein
      pfam16208
      Location:16169
      Keratin_2_head; Keratin type II head
      cl12013
      Location:217372
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl23720
      Location:390452
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      101433461..101441255 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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