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    Zfp2 zinc finger protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 22678, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zfp2provided by MGI
    Official Full Name
    zinc finger protein 2provided by MGI
    Primary source
    MGI:MGI:99167
    See related
    Ensembl:ENSMUSG00000049321
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fnp; Zfp-; mKR2; mkr-; Fnp-2; Zfp-2; mkr-2; mszf87; 9930007F06Rik
    Expression
    Broad expression in CNS E18 (RPKM 2.3), whole brain E14.5 (RPKM 2.2) and 20 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp2 in Genome Data Viewer
    Location:
    11 B1.3; 11 30.94 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (50788092..50807043, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (50897265..50916216, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (50712214..50729663, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene glutamate receptor, metabotropic 6 Neighboring gene zinc finger protein 454 Neighboring gene zinc finger protein 354B Neighboring gene RIKEN cDNA 4933414I15 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Clone Names

    • MGC107189

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044697.2NP_001038162.1  zinc finger protein 2

      See identical proteins and their annotated locations for NP_001038162.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 2. Variants 2, 3, 4, 6 and 7 encode the same protein.
      Source sequence(s)
      AK141471, BC052029, BY107004
      Consensus CDS
      CCDS36148.1
      UniProtKB/Swiss-Prot
      P08043
      Related
      ENSMUSP00000112079.2, ENSMUST00000116378.8
      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001044698.2NP_001038163.1  zinc finger protein 2

      See identical proteins and their annotated locations for NP_001038163.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 2. Variants 2, 3, 4, 6 and 7 encode the same protein.
      Source sequence(s)
      AK141471, BC052029, BY107004
      Consensus CDS
      CCDS36148.1
      UniProtKB/Swiss-Prot
      P08043
      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_001044700.2NP_001038165.1  zinc finger protein 2

      See identical proteins and their annotated locations for NP_001038165.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 2. Variants 2, 3, 4, 6 and 7 encode the same protein.
      Source sequence(s)
      BC052029, BC089506, BY107004
      Consensus CDS
      CCDS36148.1
      UniProtKB/Swiss-Prot
      P08043
      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. NM_001294323.1NP_001281252.1  zinc finger protein 2

      See identical proteins and their annotated locations for NP_001281252.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 2. Variants 2, 3, 4, 6 and 7 encode the same protein.
      Source sequence(s)
      AL627215, BC052029, BY107004, CJ044064
      Consensus CDS
      CCDS36148.1
      UniProtKB/Swiss-Prot
      P08043
      Related
      ENSMUSP00000104757.2, ENSMUST00000109129.8
      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. NM_178447.3NP_848542.1  zinc finger protein 2

      See identical proteins and their annotated locations for NP_848542.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longest transcript. Variants 2, 3, 4, 6 and 7 encode the same protein.
      Source sequence(s)
      AL627215, BC052029, BY107004
      Consensus CDS
      CCDS36148.1
      UniProtKB/Swiss-Prot
      P08043
      Related
      ENSMUSP00000104756.2, ENSMUST00000109128.8
      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      50788092..50807043 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314506.2XP_017169995.1  zinc finger protein 2 isoform X2

      UniProtKB/Swiss-Prot
      P08043
      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_030245935.2XP_030101795.1  zinc finger protein 2 isoform X1

      Conserved Domains (2) summary
      COG5048
      Location:131484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:417437
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. XM_030245940.1XP_030101800.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. XM_036156640.1XP_036012533.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. XM_036156638.1XP_036012531.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. XM_036156639.1XP_036012532.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    7. XM_030245936.1XP_030101796.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    8. XM_036156637.1XP_036012530.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    9. XM_030245938.1XP_030101798.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    10. XM_030245941.1XP_030101801.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    11. XM_030245937.2XP_030101797.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]
    12. XM_030245939.2XP_030101799.1  zinc finger protein 2 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:96449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382402
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001044699.1: Suppressed sequence

      Description
      NM_001044699.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
    2. NM_009550.1: Suppressed sequence

      Description
      NM_009550.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
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