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    Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII [ Mus musculus (house mouse) ]

    Gene ID: 22272, updated on 23-Jun-2021

    Summary

    Official Symbol
    Uqcrqprovided by MGI
    Official Full Name
    ubiquinol-cytochrome c reductase, complex III subunit VIIprovided by MGI
    Primary source
    MGI:MGI:107807
    See related
    Ensembl:ENSMUSG00000044894
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Qp; QP-; Qpc; QP-C; Uqcrb; c1502; 9.5kDa; AA959903; 1100001F06Rik; 1500040F11Rik; 5830407L17Rik
    Expression
    Ubiquitous expression in duodenum adult (RPKM 291.7), liver adult (RPKM 266.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Uqcrq in Genome Data Viewer
    Location:
    11; 11 B1.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (53318749..53321658, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (53427922..53430831, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (53242450..53244333, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene AF4/FMR2 family, member 4 Neighboring gene microRNA 6920 Neighboring gene liver-expressed antimicrobial peptide 2 Neighboring gene growth differentiation factor 9 Neighboring gene predicted gene, 30585

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ubiquinol-cytochrome-c reductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane HDA PubMed 
    part_of mitochondrial respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in respirasome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytochrome b-c1 complex subunit 8
    Names
    complex III subunit 8
    complex III subunit VII
    complex III subunit VIII
    low molecular mass ubiquinone-binding protein (Qpc-pending)
    ubiquinol-cytochrome c reductase binding protein
    ubiquinol-cytochrome c reductase complex 9.5 kDa protein
    ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
    NP_001313543.1
    NP_079628.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001326614.1NP_001313543.1  cytochrome b-c1 complex subunit 8

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK003160, AK005374, AL592489, CB950804
      Consensus CDS
      CCDS36151.1
      UniProtKB/Swiss-Prot
      Q9CQ69
      Related
      ENSMUSP00000104649.4, ENSMUST00000109021.4
      Conserved Domains (1) summary
      pfam02939
      Location:479
      UcrQ; UcrQ family
    2. NM_025352.3NP_079628.1  cytochrome b-c1 complex subunit 8

      See identical proteins and their annotated locations for NP_079628.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein
      Source sequence(s)
      AK005374, AK007982, AL592489, CB950804
      Consensus CDS
      CCDS36151.1
      UniProtKB/Swiss-Prot
      Q9CQ69
      Related
      ENSMUSP00000053145.5, ENSMUST00000061326.5
      Conserved Domains (1) summary
      pfam02939
      Location:479
      UcrQ; UcrQ family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      53318749..53321658 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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