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    Tmem65 transmembrane protein 65 [ Mus musculus (house mouse) ]

    Gene ID: 74868, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tmem65provided by MGI
    Official Full Name
    transmembrane protein 65provided by MGI
    Primary source
    MGI:MGI:1922118
    See related
    Ensembl:ENSMUSG00000062373
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610029O13Rik; 4930438D12Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 30.6), cerebellum adult (RPKM 15.8) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Tmem65 in Genome Data Viewer
    Location:
    15; 15 D1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (58654118..58695510, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (58782269..58823663, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (58613824..58654982, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene fer-1-like 6 (C. elegans) Neighboring gene predicted gene, 36451 Neighboring gene predicted gene, 41329 Neighboring gene predicted gene, 24041 Neighboring gene tRNA methyltransferase 12 Neighboring gene predicted gene, 36509

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cardiac ventricle development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cardiac ventricle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cardiac conduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of cardiac conduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intercalated disc IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intercalated disc ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175212.4NP_780421.2  transmembrane protein 65

      See identical proteins and their annotated locations for NP_780421.2

      Status: PROVISIONAL

      Source sequence(s)
      AC107772
      Consensus CDS
      CCDS27493.1
      UniProtKB/Swiss-Prot
      Q4VAE3
      Related
      ENSMUSP00000071984.6, ENSMUST00000072113.6
      Conserved Domains (1) summary
      pfam10507
      Location:114221
      DUF2453; Protein of unknown function (DUF2453)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      58654118..58695510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521504.5XP_006521567.1  transmembrane protein 65 isoform X1

      Conserved Domains (1) summary
      pfam10507
      Location:141248
      TMEM65; Transmembrane protein 65
    2. XM_036159621.1XP_036015514.1  transmembrane protein 65 isoform X2

      Conserved Domains (1) summary
      pfam10507
      Location:36143
      TMEM65; Transmembrane protein 65
    3. XM_011245759.4XP_011244061.1  transmembrane protein 65 isoform X3

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