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    Trappc13 trafficking protein particle complex 13 [ Mus musculus (house mouse) ]

    Gene ID: 66975, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Trappc13provided by MGI
    Official Full Name
    trafficking protein particle complex 13provided by MGI
    Primary source
    MGI:MGI:1914225
    See related
    Ensembl:ENSMUSG00000021711 AllianceGenome:MGI:1914225
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410002O22Rik; 2610524F24Rik
    Summary
    Predicted to be part of TRAPPIII protein complex. Orthologous to human TRAPPC13 (trafficking protein particle complex subunit 13). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 6.3), cortex adult (RPKM 5.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Trappc13 in Genome Data Viewer
    Location:
    13 D1; 13 56.28 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (104278661..104314974, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (104142153..104178466, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene neurolysin (metallopeptidase M3 family) Neighboring gene STARR-seq mESC enhancer starr_35530 Neighboring gene predicted gene, 30967 Neighboring gene STARR-positive B cell enhancer mm9_chr13:104881886-104882187 Neighboring gene small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta Neighboring gene STARR-positive B cell enhancer ABC_E3099 Neighboring gene STARR-positive B cell enhancer ABC_E8896 Neighboring gene STARR-positive B cell enhancer ABC_E385 Neighboring gene STARR-seq mESC enhancer starr_35535 Neighboring gene shieldin complex subunit 3 Neighboring gene tripartite motif-containing 23 Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E4090

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. TRAPP Complexes in Secretion and Autophagy. Kim JJ, et al. Front Cell Dev Biol, 2016. PMID 27066478, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in vesicle coating NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in vesicle tethering NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TRAPPII protein complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of TRAPPIII protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trafficking protein particle complex subunit 13
    Names
    UPF0533 protein C5orf44 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001093759.1 → NP_001087228.1  trafficking protein particle complex subunit 13 isoform 2

      See identical proteins and their annotated locations for NP_001087228.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2).
      Source sequence(s)
      AC154216, AK084373, AK149832, CF586080
      Consensus CDS
      CCDS49352.1
      UniProtKB/Swiss-Prot
      Q3TIR1, Q3TQS3, Q3UE00, Q8BN93, Q8VDJ6, Q9CWW3, Q9CXV2
      UniProtKB/TrEMBL
      J3QNW4
      Related
      ENSMUSP00000118316.2, ENSMUST00000141557.8
      Conserved Domains (1) summary
      pfam06159
      Location:65 → 297
      DUF974; Protein of unknown function (DUF974)

    2. NM_001093760.1 → NP_001087229.1  trafficking protein particle complex subunit 13 isoform 3

      See identical proteins and their annotated locations for NP_001087229.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in a shorter protein (isoform 3).
      Source sequence(s)
      AC154216, AK149832, AK163342, CF586080
      Consensus CDS
      CCDS49351.1
      UniProtKB/TrEMBL
      J3QNW4
      Related
      ENSMUSP00000114406.2, ENSMUST00000144060.8
      Conserved Domains (1) summary
      pfam06159
      Location:65 → 291
      DUF974; Protein of unknown function (DUF974)

    3. NM_001360778.1 → NP_001347707.1  trafficking protein particle complex subunit 13 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC154216
      UniProtKB/TrEMBL
      J3QNW4
      Conserved Domains (1) summary
      pfam06159
      Location:65 → 292
      DUF974; Protein of unknown function (DUF974)

    4. NM_025879.2 → NP_080155.3  trafficking protein particle complex subunit 13 isoform 1

      See identical proteins and their annotated locations for NP_080155.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC154216, AK013956, AK149832, CF586080
      Consensus CDS
      CCDS49353.1
      UniProtKB/TrEMBL
      J3QNW4
      Related
      ENSMUSP00000022224.10, ENSMUST00000022224.16
      Conserved Domains (1) summary
      pfam06159
      Location:65 → 297
      DUF974; Protein of unknown function (DUF974)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      104278661..104314974 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_003546.1: Suppressed sequence

      Description
      NR_003546.1: This RefSeq was removed because it is now thought that this transcript represents a coding transript on another locus, Shld3.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3TIR1.1 GenPept UniProtKB/Swiss-Prot:Q3TIR1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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