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    Mfsd4a major facilitator superfamily domain containing 4A [ Mus musculus (house mouse) ]

    Gene ID: 213006, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mfsd4aprovided by MGI
    Official Full Name
    major facilitator superfamily domain containing 4Aprovided by MGI
    Primary source
    MGI:MGI:2442786
    See related
    Ensembl:ENSMUSG00000059149
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mfsd; Mfsd4; AI850289; A230072B04; A930031D07Rik
    Expression
    Broad expression in colon adult (RPKM 40.5), adrenal adult (RPKM 15.7) and 17 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Mfsd4a in Genome Data Viewer
    Location:
    1; 1 E4
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (131947543..131997400, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (132022806..132069658, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (133923198..133964639, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene nuclear casein kinase and cyclin-dependent kinase substrate 1 Neighboring gene solute carrier family 45, member 3 Neighboring gene ELK4, member of ETS oncogene family Neighboring gene RIKEN cDNA 4833413N01 gene Neighboring gene predicted gene, 37120

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glucose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    major facilitator superfamily domain-containing protein 4A
    Names
    major facilitator superfamily domain containing 4
    major facilitator superfamily domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114662.1NP_001108134.1  major facilitator superfamily domain-containing protein 4A isoform b

      See identical proteins and their annotated locations for NP_001108134.1

      Status: VALIDATED

      Source sequence(s)
      AC107837, AI642828, AK048692, AK085484, AK162495
      Consensus CDS
      CCDS48357.1
      UniProtKB/Swiss-Prot
      Q6PDC8
      Related
      ENSMUSP00000125558.2, ENSMUST00000159038.8
      Conserved Domains (2) summary
      cd06174
      Location:298480
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:22442
      MFS_1; Major Facilitator Superfamily
    2. NM_172510.4NP_766098.2  major facilitator superfamily domain-containing protein 4A isoform a

      See identical proteins and their annotated locations for NP_766098.2

      Status: VALIDATED

      Source sequence(s)
      AK048692, AK162495
      Consensus CDS
      CCDS15280.2
      UniProtKB/Swiss-Prot
      Q6PDC8
      Related
      ENSMUSP00000107989.3, ENSMUST00000112370.9
      Conserved Domains (1) summary
      cd17453
      Location:18479
      MFS_MFSD4A; Major facilitator superfamily domain-containing protein 4A

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      131947543..131997400 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529345.5XP_006529408.1  major facilitator superfamily domain-containing protein 4A isoform X2

      See identical proteins and their annotated locations for XP_006529408.1

      UniProtKB/Swiss-Prot
      Q6PDC8
      Conserved Domains (1) summary
      cl28910
      Location:1257
      MFS; Major Facilitator Superfamily
    2. XM_030252744.2XP_030108604.1  major facilitator superfamily domain-containing protein 4A isoform X1

      Related
      ENSMUSP00000116282.3, ENSMUST00000144548.9
      Conserved Domains (1) summary
      cd17453
      Location:18479
      MFS_MFSD4A; Major facilitator superfamily domain-containing protein 4A
    3. XM_017319650.3XP_017175139.1  major facilitator superfamily domain-containing protein 4A isoform X2

      UniProtKB/Swiss-Prot
      Q6PDC8
      Conserved Domains (1) summary
      cl28910
      Location:1257
      MFS; Major Facilitator Superfamily
    4. XM_006529344.5XP_006529407.1  major facilitator superfamily domain-containing protein 4A isoform X1

      See identical proteins and their annotated locations for XP_006529407.1

      UniProtKB/Swiss-Prot
      Q6PDC8
      Related
      ENSMUSP00000116706.2, ENSMUST00000126927.8
      Conserved Domains (1) summary
      cd17453
      Location:18479
      MFS_MFSD4A; Major facilitator superfamily domain-containing protein 4A
    5. XM_030252750.2XP_030108610.1  major facilitator superfamily domain-containing protein 4A isoform X3

      Conserved Domains (1) summary
      cl28910
      Location:1257
      MFS; Major Facilitator Superfamily

    RNA

    1. XR_001783717.3 RNA Sequence

    2. XR_001783716.3 RNA Sequence

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