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    Zfp454 zinc finger protein 454 [ Mus musculus (house mouse) ]

    Gene ID: 237758, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zfp454provided by MGI
    Official Full Name
    zinc finger protein 454provided by MGI
    Primary source
    MGI:MGI:2679253
    See related
    Ensembl:ENSMUSG00000048728
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B230342N19
    Expression
    Biased expression in CNS E11.5 (RPKM 2.3), CNS E14 (RPKM 2.1) and 11 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp454 in Genome Data Viewer
    Location:
    11; 11 B1.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (50763545..50778463, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (50872718..50887634, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (50686224..50700945, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 879 Neighboring gene glutamate receptor, metabotropic 6 Neighboring gene zinc finger protein 2 Neighboring gene zinc finger protein 354B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Clone Names

    • MGC57560

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359531.1NP_001346460.1  zinc finger protein 454 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, uses an alternate start codon and lacks three coding exons, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AK046117, BC049793
      Conserved Domains (2) summary
      COG5048
      Location:135447
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:259279
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001382449.1NP_001369378.1  zinc finger protein 454 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Conserved Domains (3) summary
      smart00349
      Location:1466
      KRAB; krueppel associated box
      COG5048
      Location:196531
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:343363
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_001382450.1NP_001369379.1  zinc finger protein 454 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Conserved Domains (3) summary
      smart00349
      Location:1466
      KRAB; krueppel associated box
      COG5048
      Location:196531
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:343363
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. NM_001382451.1NP_001369380.1  zinc finger protein 454 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Related
      ENSMUSP00000129125.2, ENSMUST00000163301.8
      Conserved Domains (3) summary
      smart00349
      Location:1467
      KRAB; krueppel associated box
      COG5048
      Location:197532
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:344364
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. NM_001382452.1NP_001369381.1  zinc finger protein 454 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Conserved Domains (2) summary
      COG5048
      Location:163498
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:310330
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. NM_001382453.1NP_001369382.1  zinc finger protein 454 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Conserved Domains (2) summary
      COG5048
      Location:163498
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:310330
      ZF_C2H2; C2H2 Zn finger [structural motif]
    7. NM_001382454.1NP_001369383.1  zinc finger protein 454 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Conserved Domains (2) summary
      COG5048
      Location:133468
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:280300
      ZF_C2H2; C2H2 Zn finger [structural motif]
    8. NM_001382455.1NP_001369384.1  zinc finger protein 454 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Conserved Domains (2) summary
      COG5048
      Location:133468
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:280300
      ZF_C2H2; C2H2 Zn finger [structural motif]
    9. NM_001382456.1NP_001369385.1  zinc finger protein 454 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Conserved Domains (2) summary
      COG5048
      Location:142477
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:289309
      ZF_C2H2; C2H2 Zn finger [structural motif]
    10. NM_001382457.1NP_001369386.1  zinc finger protein 454 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL627215
      Conserved Domains (2) summary
      COG5048
      Location:164499
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:311331
      ZF_C2H2; C2H2 Zn finger [structural motif]
    11. NM_172794.3NP_766382.2  zinc finger protein 454 isoform 1

      See identical proteins and their annotated locations for NP_766382.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK046117, BC049793
      Consensus CDS
      CCDS24639.1
      UniProtKB/TrEMBL
      Q80Y34
      Related
      ENSMUSP00000061824.7, ENSMUST00000050595.13
      Conserved Domains (3) summary
      smart00349
      Location:1467
      KRAB; krueppel associated box
      COG5048
      Location:197532
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:344364
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      50763545..50778463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245962.2XP_030101822.1  zinc finger protein 454 isoform X1

      Conserved Domains (2) summary
      COG5048
      Location:135447
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:259279
      ZF_C2H2; C2H2 Zn finger [structural motif]
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