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    Mpv17l Mpv17 transgene, kidney disease mutant-like [ Mus musculus (house mouse) ]

    Gene ID: 93734, updated on 6-May-2021

    Summary

    Official Symbol
    Mpv17lprovided by MGI
    Official Full Name
    Mpv17 transgene, kidney disease mutant-likeprovided by MGI
    Primary source
    MGI:MGI:2135951
    See related
    Ensembl:ENSMUSG00000022679
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    M-; M-LP
    Expression
    Biased expression in kidney adult (RPKM 40.0), cortex adult (RPKM 5.6) and 3 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Mpv17l in Genome Data Viewer
    Location:
    16; 16 A1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (13721025..13767483)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (13903161..13949619)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (13940788..13949450)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene N-terminal Asn amidase Neighboring gene pyridoxal-dependent decarboxylase domain containing 1 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene Neighboring gene laminin, gamma 1 pseudogene Neighboring gene interferon induced transmembrane protein 7 Neighboring gene bMERB domain containing 1 Neighboring gene aldo-keto reductase family 1, member B8 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001289561.1NP_001276490.1  mpv17-like protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice in the 3' coding region which results in a frameshift compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC107769
      Consensus CDS
      CCDS79425.1
      UniProtKB/TrEMBL
      D3Z6M3
      Related
      ENSMUSP00000116147.2, ENSMUST00000143697.8
    2. NM_001289562.1NP_001276491.1  mpv17-like protein isoform 3

      See identical proteins and their annotated locations for NP_001276491.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC107769, AK136449
      Consensus CDS
      CCDS79423.1
      UniProtKB/Swiss-Prot
      Q99MS3
      Related
      ENSMUSP00000120169.2, ENSMUST00000128757.8
      Conserved Domains (1) summary
      pfam04117
      Location:968
      Mpv17_PMP22; Mpv17 / PMP22 family
    3. NM_001289563.1NP_001276492.1  mpv17-like protein isoform 4

      See identical proteins and their annotated locations for NP_001276492.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (4) has a shorter N-terminus, compared to isoform 1. Variants 4, 5 and 6 encode the same isoform (4).
      Source sequence(s)
      AC107769, AK144372
      Consensus CDS
      CCDS79426.1
      UniProtKB/Swiss-Prot
      Q99MS3
      Related
      ENSMUSP00000123424.2, ENSMUST00000141971.8
      Conserved Domains (1) summary
      pfam04117
      Location:261
      Mpv17_PMP22; Mpv17 / PMP22 family
    4. NM_001289565.1NP_001276494.1  mpv17-like protein isoform 4

      See identical proteins and their annotated locations for NP_001276494.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (4) has a shorter N-terminus, compared to isoform 1. Variants 4, 5 and 6 encode the same isoform (4).
      Source sequence(s)
      AC107769
      Consensus CDS
      CCDS79426.1
      UniProtKB/Swiss-Prot
      Q99MS3
      Related
      ENSMUSP00000117826.3, ENSMUST00000124947.8
      Conserved Domains (1) summary
      pfam04117
      Location:261
      Mpv17_PMP22; Mpv17 / PMP22 family
    5. NM_001289567.1NP_001276496.1  mpv17-like protein isoform 4

      See identical proteins and their annotated locations for NP_001276496.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (4) has a shorter N-terminus, compared to isoform 1. Variants 4, 5 and 6 encode the same isoform (4).
      Source sequence(s)
      AC107769, BB618586
      Consensus CDS
      CCDS79426.1
      UniProtKB/Swiss-Prot
      Q99MS3
      Conserved Domains (1) summary
      pfam04117
      Location:261
      Mpv17_PMP22; Mpv17 / PMP22 family
    6. NM_033564.3NP_291042.2  mpv17-like protein isoform 1

      See identical proteins and their annotated locations for NP_291042.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the logest isoform (1).
      Source sequence(s)
      AC107769, AF305634
      Consensus CDS
      CCDS27970.1
      UniProtKB/Swiss-Prot
      Q99MS3
      Related
      ENSMUSP00000023360.8, ENSMUST00000023360.14
      Conserved Domains (1) summary
      pfam04117
      Location:107166
      Mpv17_PMP22; Mpv17 / PMP22 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      13721025..13767483
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249342.1XP_030105202.1  mpv17-like protein isoform X1

      Conserved Domains (1) summary
      pfam04117
      Location:261
      Mpv17_PMP22; Mpv17 / PMP22 family
    2. XM_036160190.1XP_036016083.1  mpv17-like protein isoform X1

      Conserved Domains (1) summary
      pfam04117
      Location:261
      Mpv17_PMP22; Mpv17 / PMP22 family
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