Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Suclg1 succinate-CoA ligase, GDP-forming, alpha subunit [ Mus musculus (house mouse) ]

    Gene ID: 56451, updated on 23-Jun-2021

    Summary

    Official Symbol
    Suclg1provided by MGI
    Official Full Name
    succinate-CoA ligase, GDP-forming, alpha subunitprovided by MGI
    Primary source
    MGI:MGI:1927234
    See related
    Ensembl:ENSMUSG00000052738
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Suc; Sucla1; 1500000I01Rik
    Expression
    Ubiquitous expression in kidney adult (RPKM 105.3), heart adult (RPKM 103.6) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Suclg1 in Genome Data Viewer
    Location:
    6; 6 C1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (73225488..73253890)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (73248505..73276907)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (73198499..73226901)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene dynein, axonemal, heavy chain 6 Neighboring gene predicted gene, 24533 Neighboring gene predicted gene, 40377 Neighboring gene predicted gene, 38834 Neighboring gene predicted gene, 40378 Neighboring gene olfactory receptor 210, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables succinate-CoA ligase (ADP-forming) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables succinate-CoA ligase (ADP-forming) activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables succinate-CoA ligase (GDP-forming) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables succinate-CoA ligase (GDP-forming) activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in succinate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in succinyl-CoA metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tricarboxylic acid cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in tricarboxylic acid cycle ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of succinate-CoA ligase complex (ADP-forming) IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of succinate-CoA ligase complex (GDP-forming) ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Names
    SCS-alpha
    succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial
    succinyl-CoA synthetase subunit alpha
    NP_063932.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019879.3NP_063932.2  succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial precursor

      See identical proteins and their annotated locations for NP_063932.2

      Status: VALIDATED

      Source sequence(s)
      AI840979, AK005080, BY061062
      Consensus CDS
      CCDS20246.2
      UniProtKB/Swiss-Prot
      Q9WUM5
      Related
      ENSMUSP00000065113.7, ENSMUST00000064740.9
      Conserved Domains (3) summary
      PTZ00187
      Location:19344
      PTZ00187; succinyl-CoA synthetase alpha subunit; Provisional
      pfam02629
      Location:53146
      CoA_binding; CoA binding domain
      cl22543
      Location:199324
      Ligase_CoA; CoA-ligase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      73225488..73253890
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center