Taar2 trace amine-associated receptor 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Taar2provided by MGI
Official Full Name: trace amine-associated receptor 2provided by MGI
Primary source: MGI:MGI:2685071
See related: Ensembl:ENSMUSG00000059763 AllianceGenome:MGI:2685071
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm224; Gm225; Gpr58; Tarr2
Summary: Predicted to enable trace-amine receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in brain; lung; male reproductive gland or organ; and nose. Orthologous to human TAAR2 (trace amine associated receptor 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 10 A4; 10 11.4 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (23814470..23817481)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (23938572..23941583)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Previous studies reported TAAR expression in brain. This paper found TAAR expression only in olfactory epithelial cells and that each TAAR detects a unique set of amine ligands. TAARs seem to function as a family of chemosensory receptors for amines.
Title: A second class of chemosensory receptors in the olfactory epithelium.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

General gene information

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Markers

Taar2 (e-PCR), detects polymorphism
- UniSTS:516836

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled amine receptor activity	RCA inferred from Reviewed Computational Analysis more info	PubMed
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables trace-amine receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	RCA inferred from Reviewed Computational Analysis more info	PubMed
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: trace amine-associated receptor 2

Names: G protein-coupled receptor 58; mTaar2; taR-2; trace amine receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.