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    Gm5134 predicted gene 5134 [ Mus musculus (house mouse) ]

    Gene ID: 333669, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Gm5134provided by MGI
    Official Full Name
    predicted gene 5134provided by MGI
    Primary source
    MGI:MGI:3646667
    See related
    Ensembl:ENSMUSG00000033255 AllianceGenome:MGI:3646667
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG333669
    Summary
    Predicted to enable glucose:sodium symporter activity. Predicted to be involved in sodium ion transport. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 6.9), thymus adult (RPKM 1.2) and 1 other tissue See more
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    Genomic context

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    Location:
    10 C1; 10 38.63 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (75790330..75845425)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (75954496..76009591)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_27166 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 10 Neighboring gene STARR-positive B cell enhancer ABC_E11443 Neighboring gene STARR-positive B cell enhancer ABC_E5150 Neighboring gene predicted gene 867 Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene V-set pre-B cell surrogate light chain 3 Neighboring gene predicted gene, 40698 Neighboring gene STARR-seq mESC enhancer starr_27167 Neighboring gene STARR-positive B cell enhancer ABC_E8345 Neighboring gene STARR-seq mESC enhancer starr_27168 Neighboring gene microRNA 6409 Neighboring gene STARR-seq mESC enhancer starr_27169 Neighboring gene STARR-positive B cell enhancer ABC_E3892 Neighboring gene zinc finger protein 280B Neighboring gene STARR-seq mESC enhancer starr_27170 Neighboring gene STARR-seq mESC enhancer starr_27172 Neighboring gene solute carrier family 5 (neutral amino acid transporters, system A), member 4b Neighboring gene predicted gene 16222

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Post-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapment. Osipovich AB, et al. Genome Res, 2005 Mar. PMID 15741512, Free PMC Article
    2. A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Endoh-Yamagami S, et al. Dev Biol, 2010 Apr 1. PMID 20096683
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glucose:sodium symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in sodium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 5 (sodium/glucose cotransporter)-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198635.3 → NP_941037.2  solute carrier family 5 (sodium/glucose cotransporter)-like

      Status: VALIDATED

      Source sequence(s)
      AK041995, AK133270, BX523577
      Consensus CDS
      CCDS35940.2
      UniProtKB/TrEMBL
      E9QAB5, Q3V0B7
      Related
      ENSMUSP00000097172.4, ENSMUST00000099577.4
      Conserved Domains (1) summary
      cl00456
      Location:26 → 671
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      75790330..75845425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513791.4 → XP_006513854.1  solute carrier family 5 (sodium/glucose cotransporter)-like isoform X1

      UniProtKB/TrEMBL
      Q3V0B7
      Conserved Domains (1) summary
      cl00456
      Location:26 → 695
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. XM_036155860.1 → XP_036011753.1  solute carrier family 5 (sodium/glucose cotransporter)-like isoform X4

      Conserved Domains (1) summary
      cl00456
      Location:26 → 554
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. XM_036155858.1 → XP_036011751.1  solute carrier family 5 (sodium/glucose cotransporter)-like isoform X2

      UniProtKB/TrEMBL
      Q3V0B7
      Conserved Domains (1) summary
      cl00456
      Location:26 → 660
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    4. XM_036155859.1 → XP_036011752.1  solute carrier family 5 (sodium/glucose cotransporter)-like isoform X3

      UniProtKB/TrEMBL
      Q3V0B7
      Conserved Domains (1) summary
      cl00456
      Location:44 → 636
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    5. XM_036155861.1 → XP_036011754.1  solute carrier family 5 (sodium/glucose cotransporter)-like isoform X5

      Conserved Domains (1) summary
      cl00456
      Location:26 → 553
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    6. XM_036155862.1 → XP_036011755.1  solute carrier family 5 (sodium/glucose cotransporter)-like isoform X6

      Conserved Domains (1) summary
      cl00456
      Location:26 → 481
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    7. XM_011243495.4 → XP_011241797.1  solute carrier family 5 (sodium/glucose cotransporter)-like isoform X7

      Conserved Domains (1) summary
      cl00456
      Location:26 → 426
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RNA

    1. XR_004936205.1 RNA Sequence

    2. XR_871715.3 RNA Sequence

    3. XR_380409.4 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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