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    Zbtb18 zinc finger and BTB domain containing 18 [ Mus musculus (house mouse) ]

    Gene ID: 30928, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Zbtb18provided by MGI
    Official Full Name
    zinc finger and BTB domain containing 18provided by MGI
    Primary source
    MGI:MGI:1353609
    See related
    Ensembl:ENSMUSG00000063659 AllianceGenome:MGI:1353609
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RP58; Zfp238; Znf238.; zfp-238
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription, DNA-templated and skeletal muscle tissue development. Acts upstream of or within several processes, including in utero embryonic development; negative regulation of transcription by RNA polymerase II; and nervous system development. Located in nucleus. Is expressed in several structures, including genitourinary system; limb; nervous system; sensory organ; and skeleton. Used to study autosomal dominant non-syndromic intellectual disability. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 22. Orthologous to human ZBTB18 (zinc finger and BTB domain containing 18). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in cerebellum adult (RPKM 43.4), CNS E18 (RPKM 26.5) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    1 H4; 1 82.72 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (177269892..177278330)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (177442351..177450764)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene serologically defined colon cancer antigen 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:178876211-178876412 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:178880303-178880504 Neighboring gene predicted gene 15423 Neighboring gene thymoma viral proto-oncogene 3 Neighboring gene STARR-positive B cell enhancer ABC_E7781 Neighboring gene STARR-seq mESC enhancer starr_03123 Neighboring gene predicted gene, 36904 Neighboring gene STARR-positive B cell enhancer ABC_E11110 Neighboring gene STARR-positive B cell enhancer mm9_chr1:179371945-179372246 Neighboring gene STARR-positive B cell enhancer ABC_E3338 Neighboring gene keratin 8 pseudogene Neighboring gene predicted gene, 30013 Neighboring gene microRNA 12179

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis. Wang R, et al. Sci Adv, 2023 Jan 6. PMID 36608120, Free PMC Article
    2. RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortex. Ohtaka-Maruyama C, et al. Cell Rep, 2013 Feb 21. PMID 23395638
    3. The 5'-flanking region of the RP58 coding sequence shows prominent promoter activity in multipolar cells in the subventricular zone during corticogenesis. Ohtaka-Maruyama C, et al. Neuroscience, 2012 Jan 10. PMID 22119643
    4. Rp58 and p27(kip1) coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex. Clément O, et al. Neural Dev, 2017 May 15. PMID 28506232, Free PMC Article
    5. Mapping of deletion and translocation breakpoints in 1q44 implicates the serine/threonine kinase AKT3 in postnatal microcephaly and agenesis of the corpus callosum. Boland E, et al. Am J Hum Genet, 2007 Aug. PMID 17668379, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor).
      Title: Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor).
    2. The mouse model of intellectual disability by ZBTB18/RP58 haploinsufficiency shows cognitive dysfunction with synaptic impairment.
      Title: The mouse model of intellectual disability by ZBTB18/RP58 haploinsufficiency shows cognitive dysfunction with synaptic impairment.
    3. ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis.
      Title: ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis.
    4. RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons.
      Title: RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons.
    5. Findings demonstrate functional interplay between a transcriptional regulator and p27(kip1) to mediate neuroprogenitor cell cycle exit, as well as to promote radial migration through a molecular mechanism consistent with suppression of RhoA signaling.
      Title: Rp58 and p27(kip1) coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex.
    6. Disruption of RP58 expression alters the differentiation of immature neurons and impairs their migration and positioning within the mouse cerebral cortex.
      Title: The zinc finger transcription factor RP58 negatively regulates Rnd2 for the control of neuronal migration during cerebral cortical development.
    7. RP58 represses Ngn2 transcription to regulate the Ngn2-Rnd2 pathway; Ngn2 knockdown rescued migration defects of the RP58(-/-) neurons.
      Title: RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortex.
    8. Rp58 is essential for the growth and organization of the cerebellum and regulates the development of both GABAergic and glutamatergic neurons.
      Title: Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development.
    9. RP58 may act to favor neuronal differentiation and brain growth by coherently repressing multiple proneurogenic genes in a timely manner.
      Title: RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion.
    10. This study showed that Cre recombinase expression under the control of the RP58 gene promoter is a feasible tool for conditional gene switching in post-mitotic multipolar migrating young neurons in the developing cerebral cortex.
      Title: The 5'-flanking region of the RP58 coding sequence shows prominent promoter activity in multipolar cells in the subventricular zone during corticogenesis.
    Submit: New GeneRIF Correction See all GeneRIFs (16)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cerebellum development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cerebral cortex development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within hippocampus development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within homeostasis of number of cells IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within neuron development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in skeletal muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heterochromatin ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 18
    Names
    58 kDa repressor protein
    transcriptional repressor RP58
    zinc finger protein 238

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012330.2 → NP_001012330.1  zinc finger and BTB domain-containing protein 18 isoform 1

      See identical proteins and their annotated locations for NP_001012330.1

      Status: VALIDATED

      Source sequence(s)
      AC120370
      Consensus CDS
      CCDS35800.1
      UniProtKB/TrEMBL
      H7BX69
      Related
      ENSMUSP00000091831.4, ENSMUST00000094276.5
      Conserved Domains (4) summary
      COG5048
      Location:303 → 490
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:421 → 441
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:10 → 156
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:434 → 456
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001355098.2 → NP_001342027.1  zinc finger and BTB domain-containing protein 18 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC120370
      Consensus CDS
      CCDS35800.1
      UniProtKB/TrEMBL
      H7BX69
      Conserved Domains (4) summary
      COG5048
      Location:303 → 490
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:421 → 441
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:10 → 156
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:434 → 456
      zf-H2C2_2; Zinc-finger double domain

    3. NM_001355099.2 → NP_001342028.1  zinc finger and BTB domain-containing protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC120370
      Consensus CDS
      CCDS15553.1
      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6
      Conserved Domains (4) summary
      COG5048
      Location:294 → 481
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412 → 432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:1 → 147
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:425 → 447
      zf-H2C2_2; Zinc-finger double domain

    4. NM_001355100.2 → NP_001342029.1  zinc finger and BTB domain-containing protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC120370
      Consensus CDS
      CCDS15553.1
      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6
      Conserved Domains (4) summary
      COG5048
      Location:294 → 481
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412 → 432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:1 → 147
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:425 → 447
      zf-H2C2_2; Zinc-finger double domain

    5. NM_001355101.2 → NP_001342030.1  zinc finger and BTB domain-containing protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC120370
      Consensus CDS
      CCDS15553.1
      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6
      Conserved Domains (4) summary
      COG5048
      Location:294 → 481
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412 → 432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:1 → 147
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:425 → 447
      zf-H2C2_2; Zinc-finger double domain

    6. NM_001355102.2 → NP_001342031.1  zinc finger and BTB domain-containing protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC120370
      Consensus CDS
      CCDS15553.1
      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6
      Related
      ENSMUSP00000141724.2, ENSMUST00000195612.2
      Conserved Domains (4) summary
      COG5048
      Location:294 → 481
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412 → 432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:1 → 147
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:425 → 447
      zf-H2C2_2; Zinc-finger double domain

    7. NM_001355103.2 → NP_001342032.1  zinc finger and BTB domain-containing protein 18 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC120370
      Consensus CDS
      CCDS87929.1
      UniProtKB/TrEMBL
      A0A0A6YWR6, A0A0A6YY33
      Related
      ENSMUSP00000141663.2, ENSMUST00000193480.2
      Conserved Domains (1) summary
      cd18324
      Location:10 → 156
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)

    8. NM_001421570.1 → NP_001408499.1  zinc finger and BTB domain-containing protein 18 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC120370
      UniProtKB/TrEMBL
      H7BX69

    9. NM_001421571.1 → NP_001408500.1  zinc finger and BTB domain-containing protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC120370
      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6

    10. NM_001421572.1 → NP_001408501.1  zinc finger and BTB domain-containing protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC120370
      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6

    11. NM_001421573.1 → NP_001408502.1  zinc finger and BTB domain-containing protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC120370
      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6

    12. NM_001421574.1 → NP_001408503.1  zinc finger and BTB domain-containing protein 18 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC120370
      UniProtKB/TrEMBL
      A0A0A6YWR6

    13. NM_013915.4 → NP_038943.3  zinc finger and BTB domain-containing protein 18 isoform 2

      See identical proteins and their annotated locations for NP_038943.3

      Status: VALIDATED

      Source sequence(s)
      AC120370
      Consensus CDS
      CCDS15553.1
      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6
      Related
      ENSMUSP00000076463.7, ENSMUST00000077225.8
      Conserved Domains (4) summary
      COG5048
      Location:294 → 481
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412 → 432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:1 → 147
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:425 → 447
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      177269892..177278330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165663.1 → XP_036021556.1  zinc finger and BTB domain-containing protein 18 isoform X1

      UniProtKB/TrEMBL
      H7BX69
      Conserved Domains (4) summary
      COG5048
      Location:303 → 490
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:421 → 441
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:10 → 156
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:434 → 456
      zf-H2C2_2; Zinc-finger double domain

    2. XM_036165661.1 → XP_036021554.1  zinc finger and BTB domain-containing protein 18 isoform X1

      UniProtKB/TrEMBL
      H7BX69
      Conserved Domains (4) summary
      COG5048
      Location:303 → 490
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:421 → 441
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:10 → 156
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:434 → 456
      zf-H2C2_2; Zinc-finger double domain

    3. XM_036165664.1 → XP_036021557.1  zinc finger and BTB domain-containing protein 18 isoform X1

      UniProtKB/TrEMBL
      H7BX69
      Conserved Domains (4) summary
      COG5048
      Location:303 → 490
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:421 → 441
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:10 → 156
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:434 → 456
      zf-H2C2_2; Zinc-finger double domain

    4. XM_036165662.1 → XP_036021555.1  zinc finger and BTB domain-containing protein 18 isoform X1

      UniProtKB/TrEMBL
      H7BX69
      Conserved Domains (4) summary
      COG5048
      Location:303 → 490
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:421 → 441
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:10 → 156
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:434 → 456
      zf-H2C2_2; Zinc-finger double domain

    5. XM_006496889.5 → XP_006496952.1  zinc finger and BTB domain-containing protein 18 isoform X1

      See identical proteins and their annotated locations for XP_006496952.1

      UniProtKB/TrEMBL
      H7BX69
      Conserved Domains (4) summary
      COG5048
      Location:303 → 490
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:421 → 441
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:10 → 156
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:434 → 456
      zf-H2C2_2; Zinc-finger double domain

    6. XM_030254847.2 → XP_030110707.1  zinc finger and BTB domain-containing protein 18 isoform X2

      UniProtKB/Swiss-Prot
      Q3UHU9, Q7TMA6, Q80YQ4, Q9WUK6
      Conserved Domains (4) summary
      COG5048
      Location:294 → 481
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412 → 432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18324
      Location:1 → 147
      BTB_POZ_ZBTB18_RP58; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 18 (ZBTB18)
      pfam13465
      Location:425 → 447
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9WUK6.1 GenPept UniProtKB/Swiss-Prot:Q9WUK6

    Gene LinkOut

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