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    Ccdc25 coiled-coil domain containing 25 [ Mus musculus (house mouse) ]

    Gene ID: 67179, updated on 5-Mar-2024

    Summary

    Official Symbol
    Ccdc25provided by MGI
    Official Full Name
    coiled-coil domain containing 25provided by MGI
    Primary source
    MGI:MGI:1914429
    See related
    Ensembl:ENSMUSG00000022035 AllianceGenome:MGI:1914429
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NSrp70; 2610528H13Rik
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in positive regulation of cell motility. Predicted to be located in endomembrane system. Predicted to be integral component of plasma membrane. Orthologous to human CCDC25 (coiled-coil domain containing 25). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 9.9), CNS E11.5 (RPKM 9.8) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    14 D1; 14 34.36 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66074751..66104053)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65837302..65866604)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:66424601-66424784 Neighboring gene PDZ binding kinase Neighboring gene STARR-seq mESC enhancer starr_36982 Neighboring gene STARR-seq mESC enhancer starr_36983 Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2 Neighboring gene STARR-positive B cell enhancer ABC_E5449 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:66503658-66503811 Neighboring gene predicted gene, 41181 Neighboring gene predicted gene, 41182 Neighboring gene scavenger receptor class A, member 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Clone Names

    • MGC38132

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of cell motility ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endomembrane system ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 25

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145944.5NP_666056.1  coiled-coil domain-containing protein 25

      See identical proteins and their annotated locations for NP_666056.1

      Status: VALIDATED

      Source sequence(s)
      AC125058
      Consensus CDS
      CCDS27217.1
      UniProtKB/Swiss-Prot
      Q78PG9, Q9CSQ8, Q9CUF8
      UniProtKB/TrEMBL
      A0PK78
      Related
      ENSMUSP00000022614.6, ENSMUST00000022614.7
      Conserved Domains (1) summary
      pfam05670
      Location:1112
      DUF814; Domain of unknown function (DUF814)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      66074751..66104053
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)