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    Alcam activated leukocyte cell adhesion molecule [ Mus musculus (house mouse) ]

    Gene ID: 11658, updated on 23-Jun-2021

    Summary

    Official Symbol
    Alcamprovided by MGI
    Official Full Name
    activated leukocyte cell adhesion moleculeprovided by MGI
    Primary source
    MGI:MGI:1313266
    See related
    Ensembl:ENSMUSG00000022636
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BE; SC; BEN; MuS; SC1; DM-G; MuSC; CD166; AI853494; DM-GRASP
    Expression
    Broad expression in lung adult (RPKM 24.3), CNS E11.5 (RPKM 16.7) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Alcam in Genome Data Viewer
    Location:
    16; 16 B5
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (52069359..52273444, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (52248996..52453081, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (52249109..52453110, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 29686 Neighboring gene Casitas B-lineage lymphoma b Neighboring gene predicted gene, 23513 Neighboring gene predicted gene, 32597 Neighboring gene predicted gene, 41461 Neighboring gene predicted gene, 52279 Neighboring gene RIKEN cDNA 4930404A05 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC27910

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of T cell receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in immunological synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intrinsic component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001331110.1NP_001318039.1  CD166 antigen isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AC117780, AC154383, BE654940
      Consensus CDS
      CCDS84242.1
      UniProtKB/TrEMBL
      E9Q3Q6
      Related
      ENSMUSP00000129714.2, ENSMUST00000170035.8
    2. NM_009655.3NP_033785.1  CD166 antigen isoform 1 precursor

      See identical proteins and their annotated locations for NP_033785.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC154383, AK031391, AK161090, BE654940
      Consensus CDS
      CCDS37356.1
      UniProtKB/Swiss-Prot
      Q61490
      UniProtKB/TrEMBL
      Q3TTY3, Q54AJ5
      Related
      ENSMUSP00000023312.8, ENSMUST00000023312.14
      Conserved Domains (4) summary
      smart00410
      Location:255329
      IG_like; Immunoglobulin like
      pfam08205
      Location:137231
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:256313
      Ig_3; Immunoglobulin domain
      cl11960
      Location:415488
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      52069359..52273444 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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