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    Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 [ Mus musculus (house mouse) ]

    Gene ID: 244237, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Tnfrsf26provided by MGI
    Official Full Name
    tumor necrosis factor receptor superfamily, member 26provided by MGI
    Primary source
    MGI:MGI:2651928
    See related
    Ensembl:ENSMUSG00000045362 AllianceGenome:MGI:2651928
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tnfrh3; Tnfrsf24
    Summary
    Predicted to enable identical protein binding activity and protease binding activity. Predicted to be involved in TRAIL-activated apoptotic signaling pathway and positive regulation of apoptotic process. Predicted to be located in Golgi apparatus; cytosol; and membrane raft. Predicted to be active in cell surface and plasma membrane. Is expressed in several structures, including heart; hemolymphoid system gland; liver; lung; and placenta. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervical cancer; hematologic cancer (multiple); and urinary bladder cancer. Orthologous to human TNFRSF10A (TNF receptor superfamily member 10a) and TNFRSF10C (TNF receptor superfamily member 10c). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in thymus adult (RPKM 2.0), spleen adult (RPKM 1.3) and 14 other tissues See more
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    Genomic context

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    Location:
    7 F5; 7 88.26 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (143161422..143181690, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (143607685..143627845, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene cysteinyl-tRNA synthetase 1 Neighboring gene STARR-positive B cell enhancer ABC_E1098 Neighboring gene predicted gene 15580 Neighboring gene predicted gene 15579 Neighboring gene RIKEN cDNA E230032D23 gene Neighboring gene STARR-positive B cell enhancer ABC_E6618 Neighboring gene STARR-seq mESC enhancer starr_20534 Neighboring gene tumor necrosis factor receptor superfamily, member 22 Neighboring gene tumor necrosis factor receptor superfamily, member 23 Neighboring gene STARR-positive B cell enhancer ABC_E10486

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A genomic reservoir for Tnfrsf genes is developmentally regulated and imprinted in the mouse. de la Casa Esperón E, et al. Epigenetics, 2012 Jun 1. PMID 22595876, Free PMC Article
    2. Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Schneider P, et al. J Biol Chem, 2003 Feb 14. PMID 12466268
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tumor necrosis factor receptor superfamily member 26
    Names
    TNF receptor homolog 3
    tumor necrosis factor receptor superfamily, member 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175649.5 → NP_783580.1  tumor necrosis factor receptor superfamily member 26 precursor

      See identical proteins and their annotated locations for NP_783580.1

      Status: PROVISIONAL

      Source sequence(s)
      AY165628
      Consensus CDS
      CCDS40199.1
      UniProtKB/Swiss-Prot
      P83626
      UniProtKB/TrEMBL
      A7MCW7, Q3U3N2
      Related
      ENSMUSP00000054938.8, ENSMUST00000055723.9
      Conserved Domains (1) summary
      cd15837
      Location:27 → 143
      TNFRSF26; Tumor necrosis factor receptor superfamily member 26 (TNFRSF26), also known as tumor necrosis factor receptor homolog 3 (TNFRH3)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      143161422..143181690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153125.1 → XP_036009018.1  tumor necrosis factor receptor superfamily member 26 isoform X1

      UniProtKB/TrEMBL
      A7MCW7
      Conserved Domains (1) summary
      cd15837
      Location:27 → 143
      TNFRSF26; Tumor necrosis factor receptor superfamily member 26 (TNFRSF26), also known as tumor necrosis factor receptor homolog 3 (TNFRH3)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P83626.1 GenPept UniProtKB/Swiss-Prot:P83626

    Gene LinkOut

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