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    Dmtf1l cyclin D binding myb like transcription factor 1 like [ Mus musculus (house mouse) ]

    Gene ID: 237029, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Dmtf1lprovided by MGI
    Official Full Name
    cyclin D binding myb like transcription factor 1 likeprovided by MGI
    Primary source
    MGI:MGI:3045322
    See related
    Ensembl:ENSMUSG00000058670 AllianceGenome:MGI:3045322
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4932411N23Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in eye; genitourinary system; heart; and inner ear. Orthologous to human DMTF1 (cyclin D binding myb like transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    Location:
    X E3; X 49.81 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (125720085..125741627, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (126812462..126834004, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene crumbs homolog 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_47890 Neighboring gene STARR-seq mESC enhancer starr_47891 Neighboring gene STARR-seq mESC enhancer starr_47892 Neighboring gene mitogen-activated protein kinase 3 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chrX:123300154-123300455 Neighboring gene STARR-positive B cell enhancer mm9_chrX:123306453-123306754 Neighboring gene STARR-positive B cell enhancer mm9_chrX:123309767-123310068 Neighboring gene STARR-positive B cell enhancer mm9_chrX:123310242-123310543 Neighboring gene STARR-positive B cell enhancer mm9_chrX:123311522-123311823 Neighboring gene STARR-positive B cell enhancer mm9_chrX:123312146-123312447 Neighboring gene STARR-seq mESC enhancer starr_47894 Neighboring gene STARR-seq mESC enhancer starr_47895 Neighboring gene predicted gene, 23586 Neighboring gene predicted gene, 381

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. Shimizu H, et al. PLoS One, 2013. PMID 24146773, Free PMC Article
    2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Myb-like DNA-binding domain containing protein
    Names
    novel Myb-like DNA-binding domain containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177705.3 → NP_808373.1  Myb-like DNA-binding domain containing protein

      See identical proteins and their annotated locations for NP_808373.1

      Status: VALIDATED

      Source sequence(s)
      AK029976, BC117865
      Consensus CDS
      CCDS30382.1
      UniProtKB/TrEMBL
      Q8C0S0
      Related
      ENSMUSP00000079860.5, ENSMUST00000081074.5
      Conserved Domains (3) summary
      smart00717
      Location:251 → 307
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam00249
      Location:251 → 306
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam13921
      Location:205 → 261
      Myb_DNA-bind_6; Myb-like DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      125720085..125741627 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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