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    Slc5a4a solute carrier family 5, member 4a [ Mus musculus (house mouse) ]

    Gene ID: 64452, updated on 23-Jun-2021

    Summary

    Official Symbol
    Slc5a4aprovided by MGI
    Official Full Name
    solute carrier family 5, member 4aprovided by MGI
    Primary source
    MGI:MGI:1927848
    See related
    Ensembl:ENSMUSG00000020229
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SGLT3-a
    Expression
    Biased expression in duodenum adult (RPKM 18.2), small intestine adult (RPKM 11.3) and 2 other tissues See more
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    Genomic context

    See Slc5a4a in Genome Data Viewer
    Location:
    10; 10 C1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (75983285..76025099)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (76147451..76189265)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (75610196..75652010)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 5 (neutral amino acid transporters, system A), member 4b Neighboring gene predicted gene 16222 Neighboring gene solute carrier family 5 (neutral amino acid transporters, system A), member 4b pseudogene Neighboring gene ribosomal protein L32 pseudogene Neighboring gene microRNA 678 Neighboring gene protein arginine N-methyltransferase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glucose:sodium symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables proton transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables proton transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within proton transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within proton transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sodium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IC
    Inferred by Curator
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    solute carrier family 5 member 4A
    Names
    Na(+)/glucose cotransporter 3
    low affinity sodium-glucose cotransporter
    sodium-dependent glucose cotransporter
    sodium/glucose cotransporter 3
    solute carrier family 5 member 4
    solute carrier family 5, member alpha 4a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133184.2NP_573447.2  solute carrier family 5 member 4A

      See identical proteins and their annotated locations for NP_573447.2

      Status: VALIDATED

      Source sequence(s)
      AC140851
      Consensus CDS
      CCDS35941.1
      UniProtKB/TrEMBL
      G5E836
      Related
      ENSMUSP00000020450.4, ENSMUST00000020450.4
      Conserved Domains (1) summary
      cl00456
      Location:27656
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      75983285..76025099
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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