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    S1pr5 sphingosine-1-phosphate receptor 5 [ Mus musculus (house mouse) ]

    Gene ID: 94226, updated on 23-Jun-2021

    Summary

    Official Symbol
    S1pr5provided by MGI
    Official Full Name
    sphingosine-1-phosphate receptor 5provided by MGI
    Primary source
    MGI:MGI:2150641
    See related
    Ensembl:ENSMUSG00000045087
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S1; lp; Edg8; S1P5; lpB4
    Expression
    Biased expression in cerebellum adult (RPKM 10.8), stomach adult (RPKM 9.4) and 11 other tissues See more
    Orthologs
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    Genomic context

    See S1pr5 in Genome Data Viewer
    Location:
    9; 9 A3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21154213..21159739, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21242917..21248443, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21047361..21052887, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36118 Neighboring gene phosphodiesterase 4A, cAMP specific Neighboring gene kelch-like ECH-associated protein 1 Neighboring gene autophagy related 4D, cysteine peptidase Neighboring gene KRI1 homolog Neighboring gene cyclin dependent kinase inhibitor 2D

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables G protein-coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables sphingosine-1-phosphate receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    sphingosine 1-phosphate receptor 5
    Names
    S1P receptor 5
    S1P receptor Edg-8
    endothelial differentiation G-protein-coupled receptor 8
    endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
    lysophospholipid receptor B4
    sphingosine 1-phosphate receptor Edg-8
    sphingosine-1-phosphate receptor LPB4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053190.2NP_444420.1  sphingosine 1-phosphate receptor 5

      See identical proteins and their annotated locations for NP_444420.1

      Status: VALIDATED

      Source sequence(s)
      AI848371, AI852113, AK081126, BY736639
      Consensus CDS
      CCDS22898.1
      UniProtKB/Swiss-Prot
      Q91X56
      Related
      ENSMUSP00000113843.2, ENSMUST00000122088.2
      Conserved Domains (1) summary
      pfam00001
      Location:53307
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      21154213..21159739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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