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    Vpreb3 pre-B lymphocyte gene 3 [ Mus musculus (house mouse) ]

    Gene ID: 22364, updated on 23-Jun-2021

    Summary

    Official Symbol
    Vpreb3provided by MGI
    Official Full Name
    pre-B lymphocyte gene 3provided by MGI
    Primary source
    MGI:MGI:98938
    See related
    Ensembl:ENSMUSG00000000903
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Vpre; 8HS-2; 8HS-20; Vpreb-3; AI528709
    Expression
    Biased expression in spleen adult (RPKM 93.8), ovary adult (RPKM 27.8) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Vpreb3 in Genome Data Viewer
    Location:
    10; 10 C1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (75778859..75785491)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (75943024..75949657)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (75411057..75412391)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 11 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 10 Neighboring gene predicted gene 867 Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene predicted gene, 40698 Neighboring gene predicted gene 5134 Neighboring gene microRNA 6409

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in immunoglobulin production IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of immunoglobulin production ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358532.1NP_001345461.1  pre-B lymphocyte protein 3 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AA189606, AC134382, AI322716
      Conserved Domains (1) summary
      cl11960
      Location:16108
      Ig; Immunoglobulin domain
    2. NM_009514.5NP_033540.1  pre-B lymphocyte protein 3 isoform 1 precursor

      See identical proteins and their annotated locations for NP_033540.1

      Status: VALIDATED

      Source sequence(s)
      AC134382, AI322716, BY708695
      Consensus CDS
      CCDS23940.1
      UniProtKB/TrEMBL
      Q61243
      Related
      ENSMUSP00000000926.3, ENSMUST00000000926.3
      Conserved Domains (2) summary
      smart00410
      Location:30115
      IG_like; Immunoglobulin like
      cl11960
      Location:30121
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      75778859..75785491
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245072.2XP_030100932.1  pre-B lymphocyte protein 3 isoform X1

      Related
      ENSMUSP00000113205.2, ENSMUST00000121151.2
      Conserved Domains (1) summary
      cl11960
      Location:37128
      Ig; Immunoglobulin domain
    2. XM_030245073.2XP_030100933.1  pre-B lymphocyte protein 3 isoform X2

      Conserved Domains (1) summary
      cl11960
      Location:27115
      Ig; Immunoglobulin domain
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