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    Olfr197 olfactory receptor 197 [ Mus musculus (house mouse) ]

    Gene ID: 258477, updated on 11-Apr-2024

    Summary

    Official Symbol
    Olfr197provided by MGI
    Official Full Name
    olfactory receptor 197provided by MGI
    Primary source
    MGI:MGI:3030031
    See related
    AllianceGenome:MGI:3030031
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MOR183-3
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene appears to represent a strain-specific polymorphic pseudogene in mouse, where some strains, including the C57BL/6 reference genome strain, have a non-functional allele, while other strains have a protein-coding allele. [provided by RefSeq, Jan 2019]
    Annotation information
    Annotation category: suggests misassembly
    Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
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    Genomic context

    See Olfr197 in Genome Data Viewer
    Location:
    16; 16 C1.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (59005919..59006844, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (59185556..59186481, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily K member 3 Neighboring gene olfactory receptor family 5 subfamily H member 26 Neighboring gene olfactory receptor family 5 subfamily AC member 16 Neighboring gene olfactory receptor family 5 subfamily AC member 17

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    PubMed 

    General protein information

    Preferred Names
    olfactory receptor 197
    Names
    GA_x54KRFPKG5P-55400292-55399363
    olfactory receptor MOR183-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146484.1NP_666695.1  olfactory receptor 197

      See identical proteins and their annotated locations for NP_666695.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the functional non-reference strain allele and encodes the full-length protein.
      Source sequence(s)
      AY073613
      UniProtKB/TrEMBL
      Q7TS41, Q8VFB8
      Conserved Domains (1) summary
      cl21561
      Location:31305
      7tm_4; Olfactory receptor

    RNA

    1. NR_160650.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1, non-coding) includes a premature stop codon and represents the non-functional allele, as in the C57BL/6 reference genome.
      Source sequence(s)
      AC121290

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      59005919..59006844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)