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    Slc35f5 solute carrier family 35, member F5 [ Mus musculus (house mouse) ]

    Gene ID: 74150, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Slc35f5provided by MGI
    Official Full Name
    solute carrier family 35, member F5provided by MGI
    Primary source
    MGI:MGI:1921400
    See related
    Ensembl:ENSMUSG00000026342 AllianceGenome:MGI:1921400
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1300003P13Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in central nervous system; embryo; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human SLC35F5 (solute carrier family 35 member F5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 30.3), placenta adult (RPKM 26.8) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    1 E2.3; 1 54.7 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (125488275..125523571)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (125560528..125595834)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35355 Neighboring gene STARR-seq mESC enhancer starr_02098 Neighboring gene STARR-seq mESC enhancer starr_02099 Neighboring gene STARR-seq mESC enhancer starr_02100 Neighboring gene STARR-positive B cell enhancer ABC_E989 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:127332331-127332599 Neighboring gene STARR-positive B cell enhancer ABC_E11082 Neighboring gene ARP3 actin-related protein 3 Neighboring gene STARR-seq mESC enhancer starr_02104 Neighboring gene STARR-positive B cell enhancer ABC_E9475 Neighboring gene STARR-seq mESC enhancer starr_02106 Neighboring gene STARR-seq mESC enhancer starr_02107 Neighboring gene STARR-seq mESC enhancer starr_02108 Neighboring gene STARR-seq mESC enhancer starr_02109 Neighboring gene STARR-seq mESC enhancer starr_02110 Neighboring gene STARR-seq mESC enhancer starr_02112 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_02113 Neighboring gene G protein-coupled receptor 39 Neighboring gene predicted gene, 41943

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
    2. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 35 member F5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356294.1 → NP_001343223.1  solute carrier family 35 member F5 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a longer and distinct N-terminus.
      Source sequence(s)
      AC157824
      Conserved Domains (1) summary
      COG0697
      Location:268 → 493
      RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]

    2. NM_028787.5 → NP_083063.2  solute carrier family 35 member F5 isoform 1

      See identical proteins and their annotated locations for NP_083063.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the shorter isoform (1).
      Source sequence(s)
      AA038985, AK145848, CJ171116
      Consensus CDS
      CCDS35694.1
      UniProtKB/Swiss-Prot
      Q8R314, Q9DBK9
      Related
      ENSMUSP00000027580.5, ENSMUST00000027580.11
      Conserved Domains (2) summary
      COG0697
      Location:246 → 471
      RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
      pfam00892
      Location:328 → 471
      EamA; EamA-like transporter family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      125488275..125523571
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529912.5 → XP_006529975.1  solute carrier family 35 member F5 isoform X1

      Conserved Domains (1) summary
      COG0697
      Location:200 → 425
      RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]

    RNA

    1. XR_001778392.3 RNA Sequence

    2. XR_004934820.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8R314.1 GenPept UniProtKB/Swiss-Prot:Q8R314

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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