Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Treml4 triggering receptor expressed on myeloid cells-like 4 [ Mus musculus (house mouse) ]

    Gene ID: 224840, updated on 23-Jun-2021

    Summary

    Official Symbol
    Treml4provided by MGI
    Official Full Name
    triggering receptor expressed on myeloid cells-like 4provided by MGI
    Primary source
    MGI:MGI:1923239
    See related
    Ensembl:ENSMUSG00000051682
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TLT4; IDCP1; TLT-4; Treml3; BB137214; 5031403H21Rik
    Expression
    Biased expression in spleen adult (RPKM 17.3), lung adult (RPKM 2.7) and 5 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Treml4 in Genome Data Viewer
    Location:
    17; 17 C
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (48571229..48582635)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (48264200..48275607)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (48403661..48414724)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52308 Neighboring gene triggering receptor expressed on myeloid cells 1 Neighboring gene Ewing sarcoma breakpoint region 1 pseudogene Neighboring gene predicted gene, 52307 Neighboring gene triggering receptor expressed on myeloid cells 3 Neighboring gene triggering receptor expressed on myeloid cells-like 2 Neighboring gene RIKEN cDNA B430306N03 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with endosome membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with lysosomal membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    trem-like transcript 4 protein
    Names
    IG-like domain containing protein IDCP1c
    triggering receptor expressed on myeloid cells-like 3
    triggering receptor expressed on myeloid cells-like 3b
    triggering receptor expressed on myeloid cells-like protein 3
    triggering receptor expressed on myeloid cells-like protein 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033922.2NP_001029094.1  trem-like transcript 4 protein isoform 1 precursor

      See identical proteins and their annotated locations for NP_001029094.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) uses alternate in-frame splice junctions at the 5' ends of two exons compared to variant 3. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 3.
      Source sequence(s)
      AC241601, AK077228, DQ186654
      Consensus CDS
      CCDS50141.1
      UniProtKB/Swiss-Prot
      Q3LRV9
      Related
      ENSMUSP00000119177.2, ENSMUST00000125426.8
      Conserved Domains (1) summary
      cd05716
      Location:35124
      Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR)
    2. NM_001163795.1NP_001157267.1  trem-like transcript 4 protein isoform 3 precursor

      See identical proteins and their annotated locations for NP_001157267.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
      Source sequence(s)
      AC241601, AK077228, AY465532
      Consensus CDS
      CCDS50139.1
      UniProtKB/TrEMBL
      D3YYN5
      Related
      ENSMUSP00000118772.2, ENSMUST00000154335.8
      Conserved Domains (1) summary
      cd05716
      Location:39128
      Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR)
    3. NM_001163796.1NP_001157268.1  trem-like transcript 4 protein isoform 4 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 3. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 3.
      Source sequence(s)
      AC241601, AK077228, AY465532
      Consensus CDS
      CCDS50140.1
      UniProtKB/TrEMBL
      D3YY88
      Related
      ENSMUSP00000120550.2, ENSMUST00000136272.8
      Conserved Domains (1) summary
      cd05716
      Location:39128
      Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR)
    4. NM_172623.2NP_766211.2  trem-like transcript 4 protein isoform 2 precursor

      See identical proteins and their annotated locations for NP_766211.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 3. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 3.
      Source sequence(s)
      AC241601, AK077228, BC117091
      Consensus CDS
      CCDS28862.1
      UniProtKB/Swiss-Prot
      Q3LRV9
      Related
      ENSMUSP00000054121.8, ENSMUST00000059873.14
      Conserved Domains (1) summary
      cd05716
      Location:39128
      Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      48571229..48582635
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524147.5XP_006524210.1  trem-like transcript 4 protein isoform X1

      Conserved Domains (1) summary
      cd05716
      Location:35124
      Ig_pIgR_like; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and similar domains
    2. XM_006524148.4XP_006524211.1  trem-like transcript 4 protein isoform X2

      Conserved Domains (1) summary
      cd05716
      Location:39128
      Ig_pIgR_like; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and similar domains
    3. XM_006524149.4XP_006524212.1  trem-like transcript 4 protein isoform X3

      UniProtKB/Swiss-Prot
      Q3LRV9
      Related
      ENSMUSP00000115290.2, ENSMUST00000153420.2
      Conserved Domains (1) summary
      cd05716
      Location:39128
      Ig_pIgR_like; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and similar domains
    Support Center