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    Apol7c apolipoprotein L 7c [ Mus musculus (house mouse) ]

    Gene ID: 108956, updated on 8-Feb-2024

    Summary

    Official Symbol
    Apol7cprovided by MGI
    Official Full Name
    apolipoprotein L 7cprovided by MGI
    Primary source
    MGI:MGI:1920912
    See related
    Ensembl:ENSMUSG00000044309 AllianceGenome:MGI:1920912
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2210421G13Rik
    Summary
    Predicted to enable chloride channel activity and lipid binding activity. Predicted to be located in extracellular space and intracellular membrane-bounded organelle. Predicted to be part of high-density lipoprotein particle and very-low-density lipoprotein particle. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis and schizophrenia. Orthologous to several human genes including APOL1 (apolipoprotein L1); APOL2 (apolipoprotein L2); and APOL3 (apolipoprotein L3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in large intestine adult (RPKM 17.2), spleen adult (RPKM 13.7) and 8 other tissues See more
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    Genomic context

    Location:
    15 D3; 15 36.4 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (77409052..77417540, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (77524852..77533335, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene apolipoprotein L 10A Neighboring gene apolipoprotein L 11a Neighboring gene STARR-seq mESC enhancer starr_39107 Neighboring gene RIKEN cDNA 1700025B11 gene Neighboring gene apolipoprotein L 10B Neighboring gene STARR-seq mESC enhancer starr_39108

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175391.4NP_780600.1  apolipoprotein L 7c

      See identical proteins and their annotated locations for NP_780600.1

      Status: PROVISIONAL

      Source sequence(s)
      AL591864
      Consensus CDS
      CCDS37127.1
      UniProtKB/TrEMBL
      Q8C6E1
      Related
      ENSMUSP00000050745.6, ENSMUST00000062562.7
      Conserved Domains (1) summary
      pfam05461
      Location:20367
      ApoL; Apolipoprotein L

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      77409052..77417540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520277.5XP_006520340.1  apolipoprotein L 7c isoform X1

      See identical proteins and their annotated locations for XP_006520340.1

      UniProtKB/TrEMBL
      Q8C6E1
      Conserved Domains (1) summary
      pfam05461
      Location:20367
      ApoL; Apolipoprotein L