Ankrd22 ankyrin repeat domain 22 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ankrd22provided by MGI
Official Full Name: ankyrin repeat domain 22provided by MGI
Primary source: MGI:MGI:1277101
See related: Ensembl:ENSMUSG00000024774 AllianceGenome:MGI:1277101
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D19Ertd675e; 5430429D21Rik
Summary: Is expressed in eye. Orthologous to human ANKRD22 (ankyrin repeat domain 22). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in bladder adult (RPKM 6.5), liver E18 (RPKM 1.6) and 6 other tissues See more
Orthologs: human all
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Genomic context

Location:: 19 C1; 19 29.33 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (34099949..34143441, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (34122549..34166041, complement)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ANKRD22 Drives Rapid Proliferation of Lgr5(+) Cells and Acts as a Promising Therapeutic Target in Gastric Mucosal Injury.
Title: ANKRD22 Drives Rapid Proliferation of Lgr5(+) Cells and Acts as a Promising Therapeutic Target in Gastric Mucosal Injury.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (4)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: ankyrin repeat domain-containing protein 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_024204.6 → NP_077166.4 ankyrin repeat domain-containing protein 22

See identical proteins and their annotated locations for NP_077166.4

Status: VALIDATED

Source sequence(s)

AC165239

Consensus CDS

CCDS37963.1

UniProtKB/Swiss-Prot

Q9CZ89, Q9D3I2, Q9D3J5

Related

ENSMUSP00000025686.8, ENSMUST00000025686.9

Conserved Domains (4) summary

cd00204
Location:39 → 187

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:44 → 165

Ank_2; Ankyrin repeats (3 copies)

pfam13637
Location:5 → 60

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:39 → 70

ANK; ANK repeat [structural motif]