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    Gng11 guanine nucleotide binding protein (G protein), gamma 11 [ Mus musculus (house mouse) ]

    Gene ID: 66066, updated on 11-Apr-2024

    Summary

    Official Symbol
    Gng11provided by MGI
    Official Full Name
    guanine nucleotide binding protein (G protein), gamma 11provided by MGI
    Primary source
    MGI:MGI:1913316
    See related
    Ensembl:ENSMUSG00000032766 AllianceGenome:MGI:1913316
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hg3h1; 0610037B21Rik
    Summary
    Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Is expressed in renal vasculature. Orthologous to human GNG11 (G protein subunit gamma 11). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 17.3), liver E18 (RPKM 14.5) and 26 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    6 A1; 6 1.81 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (4003987..4008445)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (4003987..4008445)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15006 Neighboring gene tissue factor pathway inhibitor 2 Neighboring gene guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 Neighboring gene RIKEN cDNA 4930528H21 gene Neighboring gene STARR-positive B cell enhancer ABC_E11732 Neighboring gene Bet1 golgi vesicular membrane trafficking protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
    Names
    heterotrimeric guanine nucleotide-binding protein 3h1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025331.2NP_079607.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11

      See identical proteins and their annotated locations for NP_079607.1

      Status: PROVISIONAL

      Source sequence(s)
      BC039062
      Consensus CDS
      CCDS39419.1
      UniProtKB/Swiss-Prot
      P61953, Q4QRN2
      Related
      ENSMUSP00000031670.9, ENSMUST00000031670.10
      Conserved Domains (1) summary
      smart00224
      Location:1273
      GGL; G protein gamma subunit-like motifs

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      4003987..4008445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)