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    Tmem44 transmembrane protein 44 [ Mus musculus (house mouse) ]

    Gene ID: 224090, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Tmem44provided by MGI
    Official Full Name
    transmembrane protein 44provided by MGI
    Primary source
    MGI:MGI:1924489
    See related
    Ensembl:ENSMUSG00000022537 AllianceGenome:MGI:1924489
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B230220N21; 1700007N03Rik; 9330161C17Rik
    Summary
    Is expressed in central nervous system; ganglia; and neural retina. Orthologous to human TMEM44 (transmembrane protein 44). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 16.0), whole brain E14.5 (RPKM 12.2) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    16 B2; 16 21.34 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (30330673..30369643, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (30511855..30550825, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene ATPase type 13A3 Neighboring gene glycoprotein 5 platelet Neighboring gene STARR-positive B cell enhancer mm9_chr16:30374407-30374708 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:30389389-30389616 Neighboring gene STARR-seq mESC enhancer starr_40576 Neighboring gene STARR-seq mESC enhancer starr_40579 Neighboring gene STARR-seq mESC enhancer starr_40580 Neighboring gene predicted gene, 52252 Neighboring gene STARR-seq mESC enhancer starr_40581 Neighboring gene STARR-seq mESC enhancer starr_40582 Neighboring gene predicted gene, 53946 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:30587870-30588053 Neighboring gene large 60S subunit nuclear export GTPase 1 Neighboring gene STARR-positive B cell enhancer ABC_E5536 Neighboring gene family with sequence similarity 43, member A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 44

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357413.1 → NP_001344342.1  transmembrane protein 44 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC104885

    2. NM_001357414.1 → NP_001344343.1  transmembrane protein 44 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC104885

    3. NM_001357415.1 → NP_001344344.1  transmembrane protein 44 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC104885

    4. NM_001361297.1 → NP_001348226.1  transmembrane protein 44 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AK048655, AK082652, BC059216, BC080307, CV562351
      Related
      ENSMUST00000144491.8

    5. NM_001384248.1 → NP_001371177.1  transmembrane protein 44 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC104885

    6. NM_001384249.1 → NP_001371178.1  transmembrane protein 44 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC104885

    7. NM_001384250.1 → NP_001371179.1  transmembrane protein 44 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC104885

    8. NM_001384251.1 → NP_001371180.1  transmembrane protein 44 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC104885

    9. NM_001384252.1 → NP_001371181.1  transmembrane protein 44 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC104885

    10. NM_172614.3 → NP_766202.3  transmembrane protein 44 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC104885, AK048655
      Consensus CDS
      CCDS37310.1
      UniProtKB/TrEMBL
      E9Q4M0
      Related
      ENSMUSP00000123494.2, ENSMUST00000140402.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      30330673..30369643 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249080.1 → XP_030104940.1  transmembrane protein 44 isoform X6

    2. XM_030249077.1 → XP_030104937.1  transmembrane protein 44 isoform X2

    3. XM_030249075.2 → XP_030104935.1  transmembrane protein 44 isoform X1

    4. XM_036159894.1 → XP_036015787.1  transmembrane protein 44 isoform X7

    5. XM_030249079.2 → XP_030104939.1  transmembrane protein 44 isoform X5

    6. XM_030249078.2 → XP_030104938.1  transmembrane protein 44 isoform X4

    7. XM_036159893.1 → XP_036015786.1  transmembrane protein 44 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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