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    Catsperb cation channel sperm associated auxiliary subunit beta [ Mus musculus (house mouse) ]

    Gene ID: 271036, updated on 5-Mar-2024

    Summary

    Official Symbol
    Catsperbprovided by MGI
    Official Full Name
    cation channel sperm associated auxiliary subunit betaprovided by MGI
    Primary source
    MGI:MGI:2443988
    See related
    Ensembl:ENSMUSG00000047014 AllianceGenome:MGI:2443988
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4931410B03; 4932415G16Rik
    Summary
    Predicted to act upstream of or within sperm capacitation. Located in cilium. Part of CatSper complex. Is expressed in germ cell of testis; seminiferous tubule; spermatid; spermatocyte; and testis. Orthologous to human CATSPERB (cation channel sperm associated auxiliary subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 8.2) See more
    Orthologs
    NEW
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    Genomic context

    Location:
    12 E; 12 51.23 cM
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (101370904..101592268)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (101404645..101626009)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene cation channel, sperm-associated, beta pseudogene Neighboring gene myosin light chain, alkali, fast skeletal muscle, pseudogene Neighboring gene predicted gene, 22749 Neighboring gene STARR-seq mESC enhancer starr_33085 Neighboring gene STARR-seq mESC enhancer starr_33086 Neighboring gene predicted gene, 52022 Neighboring gene tandem C2 domains, nuclear Neighboring gene STARR-seq mESC enhancer starr_33088 Neighboring gene fibulin 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within sperm capacitation TAS
    Traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of CatSper complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of CatSper complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of monoatomic ion channel complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in sperm principal piece IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cation channel sperm-associated auxiliary subunit beta
    Names
    CatSper channel subunit beta
    catSper-beta
    cation channel sperm-associated protein subunit beta
    cation channel, sperm-associated, beta
    catsper channel auxiliary subunit beta

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173023.2NP_766611.2  cation channel sperm-associated auxiliary subunit beta precursor

      See identical proteins and their annotated locations for NP_766611.2

      Status: VALIDATED

      Source sequence(s)
      AK029843, AK030010
      Consensus CDS
      CCDS26112.1
      UniProtKB/Swiss-Prot
      A2RTF1, Q8C0R2
      Related
      ENSMUSP00000052089.4, ENSMUST00000055156.5
      Conserved Domains (1) summary
      pfam15149
      Location:5691087
      CATSPERB; Cation channel sperm-associated protein subunit beta protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      101370904..101592268
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515929.1XP_006515992.1  cation channel sperm-associated auxiliary subunit beta isoform X1

      Conserved Domains (1) summary
      pfam15149
      Location:569754
      CATSPERB; Cation channel sperm-associated protein subunit beta protein family