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    Spryd7 SPRY domain containing 7 [ Mus musculus (house mouse) ]

    Gene ID: 66674, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Spryd7provided by MGI
    Official Full Name
    SPRY domain containing 7provided by MGI
    Primary source
    MGI:MGI:1913924
    See related
    Ensembl:ENSMUSG00000021930 AllianceGenome:MGI:1913924
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Clld6; 6330409N04Rik
    Summary
    Orthologous to human SPRYD7 (SPRY domain containing 7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 6.4), cerebellum adult (RPKM 6.2) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Spryd7 in Genome Data Viewer
    Location:
    14 D1; 14 33.05 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (61769300..61794335, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (61531851..61556886, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41169 Neighboring gene RIKEN cDNA 4930556J02 gene Neighboring gene vomeronasal 1 receptor, pseudogene 136 Neighboring gene nuclear encoded tRNA lysine 32 (anticodon CTT) Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:62175814-62175923 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_36882 Neighboring gene STARR-seq mESC enhancer starr_36883 Neighboring gene tripartite motif-containing 13 Neighboring gene deleted in lymphocytic leukemia, 2 Neighboring gene potassium channel regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    SPRY domain-containing protein 7
    Names
    CLL deletion region gene 6 protein homolog
    chronic lymphocytic leukemia deletion region gene 6 protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310603.1 → NP_001297532.1  SPRY domain-containing protein 7 isoform 2

      See identical proteins and their annotated locations for NP_001297532.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK018153, AK137685, AK150789, CT009550
      Consensus CDS
      CCDS79330.1
      UniProtKB/TrEMBL
      Q3UBW1
      Related
      ENSMUSP00000098065.5, ENSMUST00000100496.5
      Conserved Domains (1) summary
      cl02614
      Location:35 → 130
      SPRY; SPRY domain

    2. NM_025697.4 → NP_079973.1  SPRY domain-containing protein 7 isoform 1

      See identical proteins and their annotated locations for NP_079973.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK018153, AK137685, CT009550
      Consensus CDS
      CCDS27185.1
      UniProtKB/Swiss-Prot
      Q3TFQ1, Q8K1Y1, Q9CU44, Q9D368, Q9D3D1
      Related
      ENSMUSP00000022497.9, ENSMUST00000022497.15
      Conserved Domains (1) summary
      cd12880
      Location:35 → 196
      SPRYD7; SPRY domain-containing protein 7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      61769300..61794335 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011245148.3 → XP_011243450.1  SPRY domain-containing protein 7 isoform X1

      Conserved Domains (1) summary
      cd12880
      Location:4 → 164
      SPRYD7; SPRY domain-containing protein 7
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3TFQ1.2 GenPept UniProtKB/Swiss-Prot:Q3TFQ1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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