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    Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 [ Mus musculus (house mouse) ]

    Gene ID: 67264, updated on 31-Jul-2021

    Summary

    Official Symbol
    Ndufb8provided by MGI
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit B8provided by MGI
    Primary source
    MGI:MGI:1914514
    See related
    Ensembl:ENSMUSG00000025204
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CI-ASHI; AI987932; 2900010I05Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 237.7), kidney adult (RPKM 174.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ndufb8 in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (44537010..44543881, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (44548571..44555442, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (44624744..44629905, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene wingless-type MMTV integration site family, member 8B Neighboring gene Sec31 homolog B (S. cerevisiae) Neighboring gene hypoxia-inducible factor 1, alpha subunit inhibitor Neighboring gene predicted gene, 35460

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables NADH dehydrogenase (ubiquinone) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables NADH dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial respiratory chain complex I assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane HDA PubMed 
    part_of mitochondrial respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mitochondrial respiratory chain complex I IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of mitochondrial respiratory chain complex I ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in respirasome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
    Names
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
    NADH-ubiquinone oxidoreductase ASHI subunit
    complex I-ASHI
    NP_001334376.1
    NP_080337.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347447.1NP_001334376.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC151478
      Consensus CDS
      CCDS84446.1
      UniProtKB/TrEMBL
      Q3V406
      Related
      ENSMUSP00000128192.2, ENSMUST00000171415.8
    2. NM_026061.3NP_080337.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial isoform 1 precursor

      See identical proteins and their annotated locations for NP_080337.1

      Status: VALIDATED

      Source sequence(s)
      AC151478
      Consensus CDS
      CCDS29851.1
      UniProtKB/Swiss-Prot
      Q9D6J5
      Related
      ENSMUSP00000026222.5, ENSMUST00000026222.11
      Conserved Domains (1) summary
      pfam05821
      Location:21186
      NDUF_B8; NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      44537010..44543881 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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