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    Unc5cl unc-5 family C-terminal like [ Mus musculus (house mouse) ]

    Gene ID: 76589, updated on 23-Jun-2021

    Summary

    Official Symbol
    Unc5clprovided by MGI
    Official Full Name
    unc-5 family C-terminal likeprovided by MGI
    Primary source
    MGI:MGI:1923839
    See related
    Ensembl:ENSMUSG00000043592
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zud; BB155270; 2510009H09Rik
    Expression
    Biased expression in duodenum adult (RPKM 18.8), small intestine adult (RPKM 18.4) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Unc5cl in Genome Data Viewer
    Location:
    17; 17 C
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (48761155..48846737)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (48454127..48539709)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (48594226..48608011)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm243 Neighboring gene translocator protein 2 Neighboring gene predicted gene, 30419 Neighboring gene predicted gene, 24071

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables netrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    UNC5C-like protein
    Names
    ZU5 and death domain-containing inhibitor of NF-kB
    ZU5 and death domain-containing protein
    protein unc-5 homolog C-like
    unc-5 homolog C-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152823.4NP_690036.4  UNC5C-like protein

      See identical proteins and their annotated locations for NP_690036.4

      Status: VALIDATED

      Source sequence(s)
      AC165291
      Consensus CDS
      CCDS28870.1
      UniProtKB/TrEMBL
      E9QLC2
      Related
      ENSMUSP00000074159.7, ENSMUST00000074574.13
      Conserved Domains (3) summary
      pfam00791
      Location:108185
      ZU5; ZU5 domain
      pfam17217
      Location:243346
      UPA; UPA domain
      cl14633
      Location:408488
      DD; Death Domain Superfamily of protein-protein interaction domains

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      48761155..48846737
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317717.2XP_017173206.1  UNC5C-like protein isoform X2

      Conserved Domains (3) summary
      pfam00791
      Location:108185
      ZU5; ZU5 domain
      pfam17217
      Location:243346
      UPA; UPA domain
      cl14633
      Location:408445
      DD; Death Domain Superfamily of protein-protein interaction domains
    2. XM_006525099.4XP_006525162.1  UNC5C-like protein isoform X1

      See identical proteins and their annotated locations for XP_006525162.1

      UniProtKB/TrEMBL
      E9QLC2
      Conserved Domains (3) summary
      pfam00791
      Location:108185
      ZU5; ZU5 domain
      pfam17217
      Location:243346
      UPA; UPA domain
      cl14633
      Location:408488
      DD; Death Domain Superfamily of protein-protein interaction domains
    3. XM_006525101.4XP_006525164.1  UNC5C-like protein isoform X3

      Conserved Domains (3) summary
      pfam00791
      Location:108185
      ZU5; ZU5 domain
      pfam17217
      Location:243346
      UPA; UPA domain
      cl14633
      Location:408445
      DD; Death Domain Superfamily of protein-protein interaction domains
    4. XM_006525102.4XP_006525165.1  UNC5C-like protein isoform X4

      See identical proteins and their annotated locations for XP_006525165.1

      Conserved Domains (2) summary
      pfam00791
      Location:108185
      ZU5; ZU5 domain
      pfam17217
      Location:243346
      UPA; UPA domain
    5. XM_006525104.4XP_006525167.1  UNC5C-like protein isoform X4

      See identical proteins and their annotated locations for XP_006525167.1

      Conserved Domains (2) summary
      pfam00791
      Location:108185
      ZU5; ZU5 domain
      pfam17217
      Location:243346
      UPA; UPA domain

    RNA

    1. XR_876580.3 RNA Sequence

    2. XR_876582.3 RNA Sequence

    3. XR_876583.3 RNA Sequence

    4. XR_385383.4 RNA Sequence

    5. XR_876584.3 RNA Sequence

    6. XR_003952210.1 RNA Sequence

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