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    Cela3b chymotrypsin-like elastase family, member 3B [ Mus musculus (house mouse) ]

    Gene ID: 67868, updated on 16-Oct-2021

    Summary

    Official Symbol
    Cela3bprovided by MGI
    Official Full Name
    chymotrypsin-like elastase family, member 3Bprovided by MGI
    Primary source
    MGI:MGI:1915118
    See related
    Ensembl:ENSMUSG00000023433
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ela3; Ela3b; AI504000; 0910001F22Rik; 2310074F01Rik
    Expression
    Biased expression in small intestine adult (RPKM 4481.6), spleen adult (RPKM 2540.8) and 2 other tissues See more
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    Genomic context

    See Cela3b in Genome Data Viewer
    Location:
    4 D3; 4 69.9 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (137148319..137157831, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (137421008..137430520, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (136976923..136986435, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31, pseudogene 10 Neighboring gene chymotrypsin-like elastase family, member 3A Neighboring gene predicted gene 13010 Neighboring gene RIKEN cDNA 1700013G24 gene Neighboring gene perlecan (heparan sulfate proteoglycan 2) Neighboring gene microRNA 7018

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables serine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix HDA PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    chymotrypsin-like elastase family member 3B
    Names
    elastase 3, pancreatic
    elastase 3B, pancreatic
    elastase IIIB
    elastase-3B
    protease E
    NP_080695.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026419.2NP_080695.1  chymotrypsin-like elastase family member 3B precursor

      See identical proteins and their annotated locations for NP_080695.1

      Status: PROVISIONAL

      Source sequence(s)
      AL645468
      Consensus CDS
      CCDS18817.1
      UniProtKB/Swiss-Prot
      Q9CQ52
      Related
      ENSMUSP00000099581.5, ENSMUST00000102522.5
      Conserved Domains (2) summary
      smart00020
      Location:27262
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:28265
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      137148319..137157831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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