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    C1qb complement component 1, q subcomponent, beta polypeptide [ Mus musculus (house mouse) ]

    Gene ID: 12260, updated on 23-Jun-2021

    Summary

    Official Symbol
    C1qbprovided by MGI
    Official Full Name
    complement component 1, q subcomponent, beta polypeptideprovided by MGI
    Primary source
    MGI:MGI:88224
    See related
    Ensembl:ENSMUSG00000036905
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Adia
    Expression
    Ubiquitous expression in mammary gland adult (RPKM 131.9), spleen adult (RPKM 123.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See C1qb in Genome Data Viewer
    Location:
    4 D3; 4 69.05 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (136607437..136613511, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (136880126..136886200, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (136436060..136442092, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene Eph receptor B2 Neighboring gene predicted gene, 52708 Neighboring gene predicted gene, 31536 Neighboring gene complement component 1, q subcomponent, C chain Neighboring gene complement component 1, q subcomponent, alpha polypeptide

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within complement activation, classical pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in complement activation, classical pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within inner ear development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in synapse pruning IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
     
    part_of complement component C1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular space HDA PubMed 
    located_in postsynapse IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    complement C1q subcomponent subunit B
    Names
    adiponectin a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009777.3NP_033907.1  complement C1q subcomponent subunit B precursor

      See identical proteins and their annotated locations for NP_033907.1

      Status: VALIDATED

      Source sequence(s)
      AL627214
      Consensus CDS
      CCDS18810.1
      UniProtKB/Swiss-Prot
      P14106
      Related
      ENSMUSP00000040246.9, ENSMUST00000046384.9
      Conserved Domains (2) summary
      pfam01391
      Location:49107
      Collagen; Collagen triple helix repeat (20 copies)
      cl23878
      Location:113250
      C1q; C1q domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      136607437..136613511 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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