Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Frs3 fibroblast growth factor receptor substrate 3 [ Mus musculus (house mouse) ]

    Gene ID: 107971, updated on 23-Jun-2021

    Summary

    Official Symbol
    Frs3provided by MGI
    Official Full Name
    fibroblast growth factor receptor substrate 3provided by MGI
    Primary source
    MGI:MGI:2135965
    See related
    Ensembl:ENSMUSG00000023266
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SN; Snt2; Frs2b; AI449674; Frs2beta; 4930417B13Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 16.9), CNS E18 (RPKM 9.5) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Frs3 in Genome Data Viewer
    Location:
    17; 17 C
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (47998532..48015211)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (47687607..47704286)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (47832156..47841235)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene 20517 Neighboring gene mediator complex subunit 20 Neighboring gene Kpna2 retrotransposed pseudogene Neighboring gene ubiquitin specific peptidase 49 Neighboring gene prickle planar cell polarity protein 4 Neighboring gene translocase of outer mitochondrial membrane 6, opposite strand Neighboring gene translocase of outer mitochondrial membrane 6 Neighboring gene fibroblast growth factor receptor substrate 3, opposite strand Neighboring gene predicted gene, 46579 Neighboring gene progastricsin (pepsinogen C)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC25496

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables fibroblast growth factor receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables fibroblast growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane receptor protein tyrosine kinase adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    fibroblast growth factor receptor substrate 3
    Names
    FGFR substrate 3
    FRS2-beta
    suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144939.2NP_659188.1  fibroblast growth factor receptor substrate 3

      See identical proteins and their annotated locations for NP_659188.1

      Status: PROVISIONAL

      Source sequence(s)
      AC124830, AC139214
      Consensus CDS
      CCDS28854.1
      UniProtKB/Swiss-Prot
      Q91WJ0
      Related
      ENSMUSP00000108921.2, ENSMUST00000113296.8
      Conserved Domains (1) summary
      cd01202
      Location:15106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      47998532..48015211
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523469.4XP_006523532.1  fibroblast growth factor receptor substrate 3 isoform X1

      See identical proteins and their annotated locations for XP_006523532.1

      UniProtKB/Swiss-Prot
      Q91WJ0
      Conserved Domains (1) summary
      cd01202
      Location:15106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain
    2. XM_006523468.3XP_006523531.1  fibroblast growth factor receptor substrate 3 isoform X1

      See identical proteins and their annotated locations for XP_006523531.1

      UniProtKB/Swiss-Prot
      Q91WJ0
      Conserved Domains (1) summary
      cd01202
      Location:15106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain
    3. XM_036160258.1XP_036016151.1  fibroblast growth factor receptor substrate 3 isoform X2

      Conserved Domains (1) summary
      cl17171
      Location:1738
      PH-like; Pleckstrin homology-like domain
    Support Center