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    Tmem234 transmembrane protein 234 [ Mus musculus (house mouse) ]

    Gene ID: 76799, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Tmem234provided by MGI
    Official Full Name
    transmembrane protein 234provided by MGI
    Primary source
    MGI:MGI:1924049
    See related
    Ensembl:ENSMUSG00000028797 AllianceGenome:MGI:1924049
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500002D11Rik; 2510006D16Rik; 4933407D05Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMEM234 (transmembrane protein 234). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 40.8), colon adult (RPKM 37.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    4 D2.2; 4 63.26 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (129494449..129502326)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (129600669..129608533)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 167, member B Neighboring gene STARR-positive B cell enhancer ABC_E11717 Neighboring gene eukaryotic translation initiation factor 3, subunit I Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:129287304-129287568 Neighboring gene doublecortin domain containing 2b Neighboring gene STARR-positive B cell enhancer ABC_E10261 Neighboring gene IQ motif containing C Neighboring gene coiled coil domain containing 28B Neighboring gene STARR-seq mESC enhancer starr_11504 Neighboring gene predicted gene, 34305

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 234

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368255.1 → NP_001355184.1  transmembrane protein 234 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AL671759
      UniProtKB/TrEMBL
      M0QWT3, Q9D484
      Related
      ENSMUSP00000137989.2, ENSMUST00000181579.8

    2. NM_001368256.1 → NP_001355185.1  transmembrane protein 234 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AL671759
      UniProtKB/TrEMBL
      Q9D484

    3. NM_001368257.1 → NP_001355186.1  transmembrane protein 234 isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AL671759
      Consensus CDS
      CCDS89832.1
      UniProtKB/TrEMBL
      G3UZQ3, Q9D484
      Related
      ENSMUSP00000134588.2, ENSMUST00000173758.8

    4. NM_001368258.1 → NP_001355187.1  transmembrane protein 234 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL671759
      UniProtKB/TrEMBL
      Q9CY44
      Conserved Domains (1) summary
      pfam10639
      Location:14 → 87
      TMEM234; Putative transmembrane family 234

    5. NM_001368259.1 → NP_001355188.1  transmembrane protein 234 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL671759
      UniProtKB/TrEMBL
      Q9CY44
      Conserved Domains (1) summary
      pfam10639
      Location:14 → 87
      TMEM234; Putative transmembrane family 234

    6. NM_001368260.1 → NP_001355189.1  transmembrane protein 234 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL671759
      Conserved Domains (1) summary
      pfam10639
      Location:5 → 74
      TMEM234; Putative transmembrane family 234

    7. NM_029748.3 → NP_084024.1  transmembrane protein 234 isoform 1 precursor

      See identical proteins and their annotated locations for NP_084024.1

      Status: VALIDATED

      Source sequence(s)
      AL671759
      Consensus CDS
      CCDS18699.1
      UniProtKB/Swiss-Prot
      Q8R1E7
      UniProtKB/TrEMBL
      Q9D484
      Related
      ENSMUSP00000099651.4, ENSMUST00000102591.10
      Conserved Domains (1) summary
      pfam10639
      Location:18 → 126
      TMEM234; Putative transmembrane family 234

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      129494449..129502326
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253888.2 → XP_030109748.1  transmembrane protein 234 isoform X2

      Conserved Domains (1) summary
      pfam10639
      Location:5 → 74
      TMEM234; Putative transmembrane family 234

    2. XM_030253889.2 → XP_030109749.1  transmembrane protein 234 isoform X3

      Conserved Domains (1) summary
      pfam10639
      Location:1 → 68
      TMEM234; Putative transmembrane family 234

    3. XM_030253885.2 → XP_030109745.1  transmembrane protein 234 isoform X1

      UniProtKB/TrEMBL
      Q9CY44
      Conserved Domains (1) summary
      pfam10639
      Location:14 → 87
      TMEM234; Putative transmembrane family 234

    4. XM_030253884.2 → XP_030109744.1  transmembrane protein 234 isoform X1

      UniProtKB/TrEMBL
      Q9CY44
      Conserved Domains (1) summary
      pfam10639
      Location:14 → 87
      TMEM234; Putative transmembrane family 234

    5. XM_030253890.2 → XP_030109750.1  transmembrane protein 234 isoform X3

      Conserved Domains (1) summary
      pfam10639
      Location:1 → 68
      TMEM234; Putative transmembrane family 234

    6. XM_030253886.2 → XP_030109746.1  transmembrane protein 234 isoform X1

      UniProtKB/TrEMBL
      Q9CY44
      Conserved Domains (1) summary
      pfam10639
      Location:14 → 87
      TMEM234; Putative transmembrane family 234

    7. XM_030253887.1 → XP_030109747.1  transmembrane protein 234 isoform X1

      UniProtKB/TrEMBL
      Q9CY44
      Conserved Domains (1) summary
      pfam10639
      Location:14 → 87
      TMEM234; Putative transmembrane family 234

    8. XM_030253891.2 → XP_030109751.1  transmembrane protein 234 isoform X3

      Conserved Domains (1) summary
      pfam10639
      Location:1 → 68
      TMEM234; Putative transmembrane family 234
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8R1E7.1 GenPept UniProtKB/Swiss-Prot:Q8R1E7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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