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    Nop16 NOP16 nucleolar protein [ Mus musculus (house mouse) ]

    Gene ID: 28126, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Nop16provided by MGI
    Official Full Name
    NOP16 nucleolar proteinprovided by MGI
    Primary source
    MGI:MGI:107862
    See related
    Ensembl:ENSMUSG00000025869 AllianceGenome:MGI:107862
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D13Wsu177e
    Summary
    Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Is expressed in embryo and extraembryonic component. Orthologous to human NOP16 (NOP16 nucleolar protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver E14 (RPKM 14.3), CNS E11.5 (RPKM 12.5) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    13 B1; 13 28.83 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (54732004..54737921, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (54584191..54590097, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene SUMO-interacting motifs containing 1 Neighboring gene RIKEN cDNA 4833439L19 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:54666808-54666917 Neighboring gene ADP-ribosylation factor-like 10 Neighboring gene predicted gene, 24195 Neighboring gene STARR-positive B cell enhancer ABC_E927 Neighboring gene HIG1 domain family, member 2A Neighboring gene clathrin light chain B Neighboring gene STARR-seq mESC enhancer starr_34588 Neighboring gene STARR-seq mESC enhancer starr_34589

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular characterizations of Nop16 in murine mammary tumors with varying levels of c-Myc. Kundel DW, et al. Transgenic Res, 2012 Apr. PMID 21863248, Free PMC Article
    2. Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis. Mikula M, et al. Proteome Sci, 2015. PMID 26336360, Free PMC Article
    3. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, et al. Hum Mol Genet, 1998 Nov. PMID 9811942
    4. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
    5. Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells. Zhang S, et al. Sci Data, 2018 Nov 20. PMID 30457570, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nucleolar protein 16
    Names
    NOP16 nucleolar protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178605.4 → NP_848720.1  nucleolar protein 16

      See identical proteins and their annotated locations for NP_848720.1

      Status: PROVISIONAL

      Source sequence(s)
      AC155262
      Consensus CDS
      CCDS26531.1
      UniProtKB/Swiss-Prot
      Q8C2P2, Q921K0, Q9CPT5
      UniProtKB/TrEMBL
      D3Z7M5
      Related
      ENSMUSP00000026987.6, ENSMUST00000026987.12
      Conserved Domains (2) summary
      pfam09420
      Location:20 → 153
      Nop16; Ribosome biogenesis protein Nop16
      cl21456
      Location:143 → 177
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      54732004..54737921 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247292.2 → XP_030103152.1  nucleolar protein 16 isoform X1

      Conserved Domains (1) summary
      pfam09420
      Location:20 → 65
      Nop16; Ribosome biogenesis protein Nop16
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CPT5.1 GenPept UniProtKB/Swiss-Prot:Q9CPT5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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