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    mrpl24 mitochondrial ribosomal protein L24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295224, updated on 3-Apr-2024

    Summary

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    Symbol
    mrpl24provided by RGD
    Full Name
    mitochondrial ribosomal protein L24provided by RGD
    Primary source
    RGD:1359289
    See related
    Ensembl:ENSRNOG00000022234 AllianceGenome:RGD:1359289
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrion. Orthologous to human MRPL24 (mitochondrial ribosomal protein L24). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 178.9), Muscle (RPKM 168.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See mrpl24 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (175680872..175687107)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173383062..173389249)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187288460..187294676)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene proline rich mitotic checkpoint control factor Neighboring gene heparin binding growth factor Neighboring gene methyltransferase like 25B Neighboring gene interferon stimulated exonuclease gene 20-like 2 Neighboring gene cellular retinoic acid binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Mammalian mitochondrial ribosomal proteins (4). Amino acid sequencing, characterization, and identification of corresponding gene sequences. O'Brien TW, et al. J Biol Chem, 2000 Jun 16. PMID 10751423
    2. Structures of the human mitochondrial ribosome in native states of assembly. Brown A, et al. Nat Struct Mol Biol, 2017 Oct. PMID 28892042, Free PMC Article
    3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
    4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94307

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    large ribosomal subunit protein uL24m
    Names
    39S ribosomal protein L24, mitochondrial
    L24mt
    MRP-L24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007637.1 → NP_001007638.1  large ribosomal subunit protein uL24m precursor

      See identical proteins and their annotated locations for NP_001007638.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082018
      UniProtKB/Swiss-Prot
      Q66H47
      UniProtKB/TrEMBL
      A6J631
      Conserved Domains (1) summary
      cl00354
      Location:59 → 154
      KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      175680872..175687107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006232604.5 → XP_006232666.1  large ribosomal subunit protein uL24m isoform X1

      See identical proteins and their annotated locations for XP_006232666.1

      UniProtKB/Swiss-Prot
      Q66H47
      UniProtKB/TrEMBL
      A6J631
      Related
      ENSRNOP00000034042.3
      Conserved Domains (1) summary
      cl00354
      Location:59 → 154
      KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

    2. XM_006232607.5 → XP_006232669.1  large ribosomal subunit protein uL24m isoform X1

      See identical proteins and their annotated locations for XP_006232669.1

      UniProtKB/Swiss-Prot
      Q66H47
      UniProtKB/TrEMBL
      A6J631
      Conserved Domains (1) summary
      cl00354
      Location:59 → 154
      KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

    3. XM_006232605.5 → XP_006232667.1  large ribosomal subunit protein uL24m isoform X1

      See identical proteins and their annotated locations for XP_006232667.1

      UniProtKB/Swiss-Prot
      Q66H47
      UniProtKB/TrEMBL
      A6J631
      Conserved Domains (1) summary
      cl00354
      Location:59 → 154
      KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

    4. XM_063281599.1 → XP_063137669.1  large ribosomal subunit protein uL24m isoform X1

      UniProtKB/Swiss-Prot
      Q66H47
      UniProtKB/TrEMBL
      A6J631

    5. XM_006232608.5 → XP_006232670.1  large ribosomal subunit protein uL24m isoform X1

      See identical proteins and their annotated locations for XP_006232670.1

      UniProtKB/Swiss-Prot
      Q66H47
      UniProtKB/TrEMBL
      A6J631
      Conserved Domains (1) summary
      cl00354
      Location:59 → 154
      KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66H47.1 GenPept UniProtKB/Swiss-Prot:Q66H47

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