Lzic leucine zipper and CTNNBIP1 domain containing [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lzicprovided by RGD
Official Full Name: leucine zipper and CTNNBIP1 domain containingprovided by RGD
Primary source: RGD:1309253
See related: AllianceGenome:RGD:1309253
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable beta-catenin binding activity. Involved in response to ionizing radiation. Biomarker of osteosarcoma. Orthologous to human LZIC (leucine zipper and CTNNBIP1 domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 58.1), Thymus (RPKM 56.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q36

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (165211359..165224569)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (159928260..159941512)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (166430305..166443485)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BE106245 (e-PCR)
- UniSTS:246189

BF391916 (e-PCR)
- UniSTS:249846

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables beta-catenin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in response to ionizing radiation	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein LZIC

Names: leucine zipper and CTNNBIP1 domain-containing protein; leucine zipper and ICAT homologous domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.