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    Mettl25b methyltransferase like 25B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361976, updated on 30-Mar-2024

    Summary

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    Official Symbol
    Mettl25bprovided by RGD
    Official Full Name
    methyltransferase like 25Bprovided by RGD
    Primary source
    RGD:1311265
    See related
    Ensembl:ENSRNOG00000011645 AllianceGenome:RGD:1311265
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rrnad1; RGD1311265
    Summary
    Predicted to be integral component of membrane. Orthologous to human METTL25B (methyltransferase like 25B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 66.6), Thymus (RPKM 62.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mettl25b in Genome Data Viewer
    Location:
    2q34
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (175686483..175695137, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173388625..173397279, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187294052..187302691, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene proline rich mitotic checkpoint control factor Neighboring gene heparin binding growth factor Neighboring gene mitochondrial ribosomal protein L24 Neighboring gene interferon stimulated exonuclease gene 20-like 2 Neighboring gene cellular retinoic acid binding protein 2 Neighboring gene nestin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    methyltransferase-like protein 25B
    Names
    protein RRNAD1
    ribosomal RNA adenine dimethylase domain containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014173.2 → NP_001014195.1  methyltransferase-like protein 25B

      See identical proteins and their annotated locations for NP_001014195.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      Q6AYG0
      Related
      ENSRNOP00000015793.4, ENSRNOT00000015793.5
      Conserved Domains (1) summary
      pfam13679
      Location:133 → 293
      Methyltransf_32; Methyltransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      175686483..175695137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006232686.5 → XP_006232748.1  methyltransferase-like protein 25B isoform X1

      See identical proteins and their annotated locations for XP_006232748.1

      UniProtKB/TrEMBL
      A6J636
      Conserved Domains (1) summary
      pfam13679
      Location:156 → 316
      Methyltransf_32; Methyltransferase domain

    2. XM_039102654.2 → XP_038958582.1  methyltransferase-like protein 25B isoform X2

      UniProtKB/TrEMBL
      A0A8I6AA49
      Conserved Domains (1) summary
      pfam13679
      Location:69 → 229
      Methyltransf_32; Methyltransferase domain

    3. XM_006232689.5 → XP_006232751.1  methyltransferase-like protein 25B isoform X3

      Conserved Domains (1) summary
      pfam13679
      Location:156 → 316
      Methyltransf_32; Methyltransferase domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AYG0.1 GenPept UniProtKB/Swiss-Prot:Q6AYG0

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