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    PRKCQ-AS1 PRKCQ antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 439949, updated on 10-Oct-2023

    Summary

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    Official Symbol
    PRKCQ-AS1provided by HGNC
    Official Full Name
    PRKCQ antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:44689
    See related
    Ensembl:ENSG00000237943 AllianceGenome:HGNC:44689
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in lymph node (RPKM 5.5), appendix (RPKM 3.6) and 18 other tissues See more
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    Genomic context

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    Location:
    10p15.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (6580425..6585361)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (6580547..6585491)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (6622387..6627323)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902370 Neighboring gene NANOG hESC enhancer GRCh37_chr10:6452056-6452557 Neighboring gene protein kinase C theta Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_13978 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_14068 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_14123 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2968 Neighboring gene uncharacterized LOC107984202 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_14215 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2108 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2109 Neighboring gene Sharpr-MPRA regulatory region 12587 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:6671711-6672282 Neighboring gene long intergenic non-protein coding RNA 2648 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:6690794-6691459 Neighboring gene NANOG hESC enhancer GRCh37_chr10:6720092-6720593 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:6778731-6779930 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:6779977-6780522 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:6780523-6781066 Neighboring gene lncRNA in non-homologous end joining pathway 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Long noncoding RNA PRKCQ-AS1 promotes CRC cell proliferation and migration via modulating miR-1287-5p/YBX1 axis. Cui G, et al. J Cell Biochem, 2020 Oct. PMID 32619070
    2. Expression Signatures of Long Noncoding RNAs in Adolescent Idiopathic Scoliosis. Liu XY, et al. Biomed Res Int, 2015. PMID 26421281, Free PMC Article
    3. Large-scale concatenation cDNA sequencing. Yu W, et al. Genome Res, 1997 Apr. PMID 9110174, Free PMC Article
    4. A "double adaptor" method for improved shotgun library construction. Andersson B, et al. Anal Biochem, 1996 Apr 5. PMID 8619474
    5. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Long noncoding RNA PRKCQ-AS1 promotes CRC cell proliferation and migration via modulating miR-1287-5p/YBX1 axis.
      Title: Long noncoding RNA PRKCQ-AS1 promotes CRC cell proliferation and migration via modulating miR-1287-5p/YBX1 axis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • ENST00000414894.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_036502.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AL158043, CN429636

    2. NR_036503.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AL158043, AY007155
      Related
      ENST00000663449.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      6580425..6585361
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      6580547..6585491
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials