RNA18SN5 RNA, 18S ribosomal N5 [Homo sapiens (human)] - Gene

Summary

Official Symbol: RNA18SN5provided by HGNC
Official Full Name: RNA, 18S ribosomal N5provided by HGNC
Primary source: HGNC:HGNC:53531
Gene type: rRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: RN18S1; RNA18S5
Summary: 45S ribosomal DNA (rDNA) arrays, or clusters, are present on human chromosomes 13, 14, 15, 21 and 22, designated RNR1 through RNR5, respectively. Each cluster consists of multiple 45S rDNA repeat units that vary in number among individuals and chromosomes, with total diploid copy number estimates ranging from 60 to >800 repeat units in a human genome. The 45S rDNA repeat unit encodes a 45S rRNA precursor, transcribed by RNA polymerase I, which is processed to form the 18S, 5.8S and 28S rRNAs. This gene is a representative copy of the 18S ribosomal RNA whose chromosomal location is unknown. [provided by RefSeq, Mar 2017]
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Genomic context

Location:: chromosome: Un

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	Unplaced Scaffold	NT_167214.1 (109078..110946)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	Unplaced Scaffold	NT_167214.1 (109078..110946)

NT_167214.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

selective inhibition of 18 S rRNA processing provokes accumulation of p53 as efficiently as abrogated 28 S rRNA maturation
Title: Defects in 18 S or 28 S rRNA processing activate the p53 pathway.

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

G47279 (e-PCR)
- UniSTS:108062

MARC_13787-13788:1024669040:1 (e-PCR)
- UniSTS:267554

PMC106412P1 (e-PCR)
- UniSTS:270119

PMC18377P1 (e-PCR)
- UniSTS:271685

PMC133845P3 (e-PCR)
- UniSTS:270670

PMC350564P1 (e-PCR)
- UniSTS:273240

PMC161419P1 (e-PCR)
- UniSTS:271451

PMC123151P1 (e-PCR)
- UniSTS:270439

PMC18810P1 (e-PCR)
- UniSTS:271733

PMC140912P1 (e-PCR)
- UniSTS:270982

PMC153210P1 (e-PCR)
- UniSTS:271251

PMC128323P1 (e-PCR)
- UniSTS:270576

Other Names

18S rRNA 5
18S ribosomal RNA
RNA, 18S ribosomal 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.