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    Rbm6 RNA binding motif protein 6 [ Mus musculus (house mouse) ]

    Gene ID: 19654, updated on 16-Oct-2021

    Summary

    Official Symbol
    Rbm6provided by MGI
    Official Full Name
    RNA binding motif protein 6provided by MGI
    Primary source
    MGI:MGI:1338037
    See related
    Ensembl:ENSMUSG00000032582
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    g16; Def-3; NY-LU-12; mKIAA4015; 4930506F14Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 17.5), CNS E14 (RPKM 14.4) and 22 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rbm6 in Genome Data Viewer
    Location:
    9; 9 F1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (107650758..107751028, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (107773559..107873358, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (107675890..107775150, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34605 Neighboring gene RNA binding motif protein 5 Neighboring gene MON1 homolog A, secretory traffciking associated Neighboring gene predicted gene, 23856

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA4015

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011251.3NP_035381.2  RNA-binding protein 6 isoform a

      See identical proteins and their annotated locations for NP_035381.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript yet it encodes the longer protein (isoform a).
      Source sequence(s)
      AK145612, BY380685, CJ155377
      Consensus CDS
      CCDS59749.1
      UniProtKB/TrEMBL
      Q3ULB0, S4R1W5
      Related
      ENSMUSP00000138400.2, ENSMUST00000183032.8
      Conserved Domains (5) summary
      cd16163
      Location:763828
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:10461079
      G-patch; G-patch domain
      pfam13599
      Location:173235
      Pentapeptide_4; Pentapeptide repeats (9 copies)
      cd12314
      Location:456533
      RRM1_RBM6; RNA recognition motif 1 (RRM1) found in vertebrate RNA-binding protein 6 (RBM6)
      cd12563
      Location:651737
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    2. NM_029169.3NP_083445.1  RNA-binding protein 6 isoform b

      See identical proteins and their annotated locations for NP_083445.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different splice site in the 5' end and uses a downstream start codon, compared to variant 1. Isoform b has a shorter N-terminus, compared to isoform a.
      Source sequence(s)
      AK145612, BY380685, CJ155377
      Consensus CDS
      CCDS23507.1
      UniProtKB/TrEMBL
      Q3ULB0
      Related
      ENSMUSP00000035201.6, ENSMUST00000035201.13
      Conserved Domains (5) summary
      cd16163
      Location:631696
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:914947
      G-patch; G-patch domain
      pfam13599
      Location:41103
      Pentapeptide_4; Pentapeptide repeats (9 copies)
      cd12563
      Location:519605
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
      cl17169
      Location:324401
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      107650758..107751028 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511651.5XP_006511714.1  RNA-binding protein 6 isoform X6

      See identical proteins and their annotated locations for XP_006511714.1

      Conserved Domains (3) summary
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    2. XM_036154729.1XP_036010622.1  RNA-binding protein 6 isoform X6

      Conserved Domains (3) summary
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    3. XM_006511650.5XP_006511713.1  RNA-binding protein 6 isoform X1

      See identical proteins and their annotated locations for XP_006511713.1

      UniProtKB/TrEMBL
      S4R1W5
      Conserved Domains (5) summary
      cd16163
      Location:763828
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:10461079
      G-patch; G-patch domain
      pfam13599
      Location:173235
      Pentapeptide_4; Pentapeptide repeats (9 copies)
      cd12314
      Location:456533
      RRM1_RBM6; RNA recognition motif 1 (RRM1) found in vertebrate RNA-binding protein 6 (RBM6)
      cd12563
      Location:651737
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    4. XM_030244144.2XP_030100004.1  RNA-binding protein 6 isoform X6

      Conserved Domains (3) summary
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    5. XM_036154726.1XP_036010619.1  RNA-binding protein 6 isoform X2

      Conserved Domains (5) summary
      cd16163
      Location:631696
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:914947
      G-patch; G-patch domain
      pfam13599
      Location:41103
      Pentapeptide_4; Pentapeptide repeats (9 copies)
      cd12563
      Location:519605
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
      cl17169
      Location:324401
      RRM_SF; RNA recognition motif (RRM) superfamily
    6. XM_017313216.2XP_017168705.1  RNA-binding protein 6 isoform X2

      UniProtKB/TrEMBL
      Q3ULB0
      Conserved Domains (5) summary
      cd16163
      Location:631696
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:914947
      G-patch; G-patch domain
      pfam13599
      Location:41103
      Pentapeptide_4; Pentapeptide repeats (9 copies)
      cd12563
      Location:519605
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
      cl17169
      Location:324401
      RRM_SF; RNA recognition motif (RRM) superfamily
    7. XM_036154725.1XP_036010618.1  RNA-binding protein 6 isoform X1

      Conserved Domains (5) summary
      cd16163
      Location:763828
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:10461079
      G-patch; G-patch domain
      pfam13599
      Location:173235
      Pentapeptide_4; Pentapeptide repeats (9 copies)
      cd12314
      Location:456533
      RRM1_RBM6; RNA recognition motif 1 (RRM1) found in vertebrate RNA-binding protein 6 (RBM6)
      cd12563
      Location:651737
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    8. XM_011242860.3XP_011241162.1  RNA-binding protein 6 isoform X6

      See identical proteins and their annotated locations for XP_011241162.1

      Conserved Domains (3) summary
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    9. XM_030244143.2XP_030100003.1  RNA-binding protein 6 isoform X4

      Conserved Domains (4) summary
      cd12563
      Location:166252
      RRM2_RBM6; RNA recognition motif 2 in vertebrate RNA-binding protein 6 (RBM6)
      cd16163
      Location:278343
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:561594
      G-patch; G-patch domain
      cl17169
      Location:1048
      RRM_SF; RNA recognition motif (RRM) superfamily
    10. XM_036154728.1XP_036010621.1  RNA-binding protein 6 isoform X5

      Conserved Domains (3) summary
      cd16163
      Location:245310
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:528561
      G-patch; G-patch domain
      cd12563
      Location:133219
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    11. XM_036154730.1XP_036010623.1  RNA-binding protein 6 isoform X6

      Conserved Domains (3) summary
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    12. XM_006511653.3XP_006511716.1  RNA-binding protein 6 isoform X6

      See identical proteins and their annotated locations for XP_006511716.1

      Conserved Domains (3) summary
      cd16163
      Location:241306
      OCRE_RBM6; OCRE domain found in RNA-binding protein 6 (RBM6) and similar proteins
      pfam01585
      Location:524557
      G-patch; G-patch domain
      cd12563
      Location:129215
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
    13. XM_036154727.1XP_036010620.1  RNA-binding protein 6 isoform X3

      Conserved Domains (3) summary
      pfam13599
      Location:173235
      Pentapeptide_4; Pentapeptide repeats (9 copies)
      cd12314
      Location:456533
      RRM1_RBM6; RNA recognition motif 1 (RRM1) found in vertebrate RNA-binding protein 6 (RBM6)
      cd12563
      Location:651737
      RRM2_RBM6; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 6 (RBM6)
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