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    Iqcd IQ motif containing D [ Mus musculus (house mouse) ]

    Gene ID: 75732, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Iqcdprovided by MGI
    Official Full Name
    IQ motif containing Dprovided by MGI
    Primary source
    MGI:MGI:1922982
    See related
    Ensembl:ENSMUSG00000029601 AllianceGenome:MGI:1922982
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933433C09Rik
    Summary
    Predicted to be located in ciliary basal body. Orthologous to human IQCD (IQ motif containing D). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 19.0), liver E14 (RPKM 1.1) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    5 F; 5 60.63 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (120724829..120745185)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (120586771..120607115)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene serine dehydratase Neighboring gene phospholipase B domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E2173 Neighboring gene solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 Neighboring gene two pore channel 1 Neighboring gene STARR-seq mESC enhancer starr_14239 Neighboring gene STARR-positive B cell enhancer ABC_E57 Neighboring gene STARR-positive B cell enhancers ABC_E2760 and ABC_E2174 Neighboring gene STARR-positive B cell enhancer ABC_E3610 Neighboring gene RBPJ interacting and tubulin associated 1 Neighboring gene DEAD box helicase 54 Neighboring gene cilia and flagella associated protein 73

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Positional cloning of the murine flavivirus resistance gene. Perelygin AA, et al. Proc Natl Acad Sci U S A, 2002 Jul 9. PMID 12080145, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dynein regulatory complex protein 10
    Names
    IQ domain-containing protein D

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029408.3 → NP_083684.1  dynein regulatory complex protein 10

      See identical proteins and their annotated locations for NP_083684.1

      Status: VALIDATED

      Source sequence(s)
      AC125183
      Consensus CDS
      CCDS19621.1
      UniProtKB/Swiss-Prot
      Q497P6, Q8C5X0, Q9D3V1
      UniProtKB/TrEMBL
      B2RPX1
      Related
      ENSMUSP00000091955.5, ENSMUST00000094391.6
      Conserved Domains (2) summary
      COG1196
      Location:201 → 394
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd22307
      Location:371 → 419
      Adgb_C_mid-like; C-terminal middle region of Androglobins (Adgbs) and related proteins; including permuted globin domain and IQ motif

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      120724829..120745185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248247.4 → XP_011246549.1  dynein regulatory complex protein 10 isoform X1

      See identical proteins and their annotated locations for XP_011246549.1

      UniProtKB/Swiss-Prot
      Q497P6, Q8C5X0, Q9D3V1
      UniProtKB/TrEMBL
      B2RPX1
      Conserved Domains (2) summary
      COG1196
      Location:201 → 394
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd22307
      Location:371 → 419
      Adgb_C_mid-like; C-terminal middle region of Androglobins (Adgbs) and related proteins; including permuted globin domain and IQ motif
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D3V1.1 GenPept UniProtKB/Swiss-Prot:Q9D3V1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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