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    pof6 F-box protein Pof6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539324, updated on 17-May-2024

    Summary

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    Gene symbol
    pof6
    Gene description
    F-box protein Pof6
    Primary source
    PomBase:SPCC18.04
    Locus tag
    SPCC18.04
    See related
    FungiDB:SPCC18.04; VEuPathDB:SPCC18.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See pof6 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (1960078..1963015)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene putative transporter Neighboring gene miscRNA Neighboring gene putative shuttle craft like transcriptional regulator Neighboring gene uncharacterized protein Neighboring gene miscRNA Neighboring gene CCR4-Not complex CAF1 family ribonuclease subunit Caf1 Neighboring gene miscRNA Neighboring gene putative oligosaccharyltransferase complex zeta subunit Ost5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Skp1 and the F-box protein Pof6 are essential for cell separation in fission yeast. Hermand D, et al. J Biol Chem, 2003 Mar 14. PMID 12511573
    2. Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast. Jourdain I, et al. Biochem J, 2009 May 13. PMID 19243310, Free PMC Article
    3. Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint. Lehmann A, et al. Genes Cells, 2004 May. PMID 15147268
    4. Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF. Tafforeau L, et al. EMBO J, 2006 Oct 4. PMID 17016471, Free PMC Article
    5. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Study identified a novel conserved protein, Sip1, as an interacting partner of an essential F-box protein Pof6.
      Title: Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin-like ligase-substrate adaptor activity ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endocytic recycling ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in septum digestion after cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytosol HDA PubMed 
    part_of exocyst IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    NOT is_active_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    F-box protein Pof6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1960078..1963015
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023374.2 → NP_588383.1  F-box protein Pof6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588383.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74854
      Conserved Domains (2) summary
      smart00256
      Location:33 → 73
      FBOX; A Receptor for Ubiquitination Targets
      pfam07393
      Location:179 → 862
      Sec10; Exocyst complex component Sec10
    Nucleotide Protein
    Heading Accession and Version

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