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    adh4 alcohol dehydrogenase Adh4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542714, updated on 11-Apr-2024

    Summary

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    Gene symbol
    adh4
    Gene description
    alcohol dehydrogenase Adh4
    Locus tag
    SPAC5H10.06c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (156430..158279, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ThiJ domain protein Neighboring gene phosphoglycerate mutase family Neighboring gene 5S ribosomal RNA Neighboring gene putative NADPH dehydrogenase Neighboring gene putative FAD binding oxidoreductase Neighboring gene uncharacterized protein Neighboring gene pantoate-beta-alanine ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A distinct type of alcohol dehydrogenase, adh4+, complements ethanol fermentation in an adh1-deficient strain of Schizosaccharomyces pombe. Sakurai M, et al. FEMS Yeast Res, 2004 Mar. PMID 15040954
    2. Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast. Corkins ME, et al. Proc Natl Acad Sci U S A, 2013 Sep 17. PMID 24003116, Free PMC Article
    3. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    4. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables alcohol dehydrogenase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alcohol dehydrogenase (NAD+) activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables alcohol dehydrogenase (NAD+) activity, zinc-dependent ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycolytic fermentation to ethanol IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    alcohol dehydrogenase Adh4
    NP_592819.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      156430..158279 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018219.2 → NP_592819.1  alcohol dehydrogenase Adh4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592819.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09669
      Conserved Domains (1) summary
      cd08176
      Location:47 → 419
      LPO; Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria
    Nucleotide Protein
    Heading Accession and Version

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