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    Defb9 defensin beta 9 [ Mus musculus (house mouse) ]

    Gene ID: 246079, updated on 23-Jun-2021

    Summary

    Official Symbol
    Defb9provided by MGI
    Official Full Name
    defensin beta 9provided by MGI
    Primary source
    MGI:MGI:2179198
    See related
    Ensembl:ENSMUSG00000047390
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BD-9
    Expression
    Restricted expression toward genital fat pad adult (RPKM 5.3) See more
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    Genomic context

    See Defb9 in Genome Data Viewer
    Location:
    8; 8 A2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22371729..22375450, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (21881713..21885434, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (22992185..22995906, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene defensin beta 2 Neighboring gene defensin beta 10 Neighboring gene defensin beta 11 Neighboring gene defensin beta 15

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Clone Names

    • MGC129393

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables CCR6 chemokine receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in defense response to Gram-negative bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in defense response to Gram-positive bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in innate immune response in mucosa IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139219.2NP_631965.1  beta-defensin 9 precursor

      See identical proteins and their annotated locations for NP_631965.1

      Status: VALIDATED

      Source sequence(s)
      BM936051
      Consensus CDS
      CCDS40286.1
      UniProtKB/Swiss-Prot
      Q8R2I6
      UniProtKB/TrEMBL
      Q32MD8
      Related
      ENSMUSP00000054085.5, ENSMUST00000057076.5
      Conserved Domains (1) summary
      pfam00711
      Location:3164
      Defensin_beta; Beta defensin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      22371729..22375450 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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