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    Slco1b2 solute carrier organic anion transporter family, member 1b2 [ Mus musculus (house mouse) ]

    Gene ID: 28253, updated on 6-May-2021

    Summary

    Official Symbol
    Slco1b2provided by MGI
    Official Full Name
    solute carrier organic anion transporter family, member 1b2provided by MGI
    Primary source
    MGI:MGI:1351899
    See related
    Ensembl:ENSMUSG00000030236
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Oatp; Slc2; mlst; OATP2; Oatp4; Slc21; lst-1; OATP-C; mlst-1; Oatp1b2; Slc21a6; Slc21a10; 7330442B20Rik
    Expression
    Biased expression in liver adult (RPKM 49.6), liver E18 (RPKM 18.8) and 1 other tissue See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slco1b2 in Genome Data Viewer
    Location:
    6 G2; 6 72.57 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (141575178..141632372)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (141629452..141686646)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (141578039..141635156)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene solute carrier organic anion transporter family, member 1c1 Neighboring gene predicted gene 5724 Neighboring gene solute carrier organic anion transporter family, member 1a4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables bile acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables bile acid transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables oligopeptide transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables organic anion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables sodium-independent organic anion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in bile acid and bile salt transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within bile acid and bile salt transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within oligopeptide transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sodium-independent organic anion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier organic anion transporter family member 1B2
    Names
    liver-specific organic anion transporter 1
    solute carrier family 21 (organic anion transporter), member 10
    solute carrier family 21 (organic anion transporter), member 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020495.2NP_065241.1  solute carrier organic anion transporter family member 1B2

      See identical proteins and their annotated locations for NP_065241.1

      Status: VALIDATED

      Source sequence(s)
      AC155326
      Consensus CDS
      CCDS20678.1
      UniProtKB/Swiss-Prot
      Q9JJL3
      Related
      ENSMUSP00000044326.7, ENSMUST00000042812.9
      Conserved Domains (1) summary
      cl28910
      Location:26557
      MFS; Major Facilitator Superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      141575178..141632372
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506963.2XP_006507026.1  solute carrier organic anion transporter family member 1B2 isoform X1

      See identical proteins and their annotated locations for XP_006507026.1

      UniProtKB/Swiss-Prot
      Q9JJL3
      Conserved Domains (1) summary
      cl28910
      Location:26557
      MFS; Major Facilitator Superfamily
    2. XM_017321611.3XP_017177100.1  solute carrier organic anion transporter family member 1B2 isoform X1

      UniProtKB/Swiss-Prot
      Q9JJL3
      Related
      ENSMUSP00000144747.2, ENSMUST00000203597.2
      Conserved Domains (1) summary
      cl28910
      Location:26557
      MFS; Major Facilitator Superfamily
    3. XM_036166208.1XP_036022101.1  solute carrier organic anion transporter family member 1B2 isoform X1

      Conserved Domains (1) summary
      cl28910
      Location:26557
      MFS; Major Facilitator Superfamily

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_178235.2: Suppressed sequence

      Description
      NM_178235.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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