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    Atxn7l1 ataxin 7-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 380753, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Atxn7l1provided by MGI
    Official Full Name
    ataxin 7-like 1provided by MGI
    Primary source
    MGI:MGI:3584458
    See related
    Ensembl:ENSMUSG00000020564 AllianceGenome:MGI:3584458
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Atxn7l4; 2810423G08Rik
    Summary
    Orthologous to human ATXN7L1 (ataxin 7 like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 6.9), thymus adult (RPKM 6.5) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    12 A3; 12 14.03 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (33196967..33426407)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (33146968..33376408)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40874 Neighboring gene predicted gene, 24922 Neighboring gene cadherin-related family member 3 Neighboring gene RIKEN cDNA F730043M19 gene Neighboring gene STARR-seq mESC enhancer starr_31887 Neighboring gene STARR-positive B cell enhancer ABC_E11509 Neighboring gene predicted gene, 38649 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:33987074-33987296 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:34000210-34000400 Neighboring gene ataxin 7-like 1, opposite strand 2 Neighboring gene STARR-seq mESC enhancer starr_31895 Neighboring gene EF-hand calcium binding domain 10 Neighboring gene STARR-seq mESC enhancer starr_31896 Neighboring gene STARR-positive B cell enhancer ABC_E2381 Neighboring gene RNA polymerase I subunit F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC28883

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ataxin-7-like protein 1
    Names
    ataxin 7-like 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033436.3 → NP_001028608.3  ataxin-7-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001028608.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1), as well as variant 7, encodes isoform 1.
      Source sequence(s)
      AC160112
      Consensus CDS
      CCDS25875.1
      UniProtKB/TrEMBL
      B2RW07, Q3U1F1
      Related
      ENSMUSP00000088085.5, ENSMUST00000090597.11
      Conserved Domains (1) summary
      pfam08313
      Location:150 → 216
      SCA7; zinc-binding domain

    2. NM_001374022.1 → NP_001360951.1  ataxin-7-like protein 1 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes the longest isoform (3).
      Source sequence(s)
      AC132312, AC132354, AC160112
      UniProtKB/TrEMBL
      F7C0E4
      Conserved Domains (1) summary
      pfam08313
      Location:274 → 340
      SCA7; zinc-binding domain

    3. NM_001374023.1 → NP_001360952.1  ataxin-7-like protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC132312, AC132354, AC160112
      UniProtKB/TrEMBL
      F6X2K7
      Conserved Domains (1) summary
      pfam08313
      Location:274 → 340
      SCA7; zinc-binding domain

    4. NM_001374024.1 → NP_001360953.1  ataxin-7-like protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC160112
      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:150 → 216
      SCA7; zinc-binding domain

    5. NM_001374025.1 → NP_001360954.1  ataxin-7-like protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC160112
      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:165 → 231
      SCA7; zinc-binding domain

    6. NM_001374026.1 → NP_001360955.1  ataxin-7-like protein 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variant 1, encodes isoform 1.
      Source sequence(s)
      AC160112
      Consensus CDS
      CCDS25875.1
      UniProtKB/TrEMBL
      B2RW07, Q3U1F1
      Related
      ENSMUSP00000122982.2, ENSMUST00000154742.2
      Conserved Domains (1) summary
      pfam08313
      Location:150 → 216
      SCA7; zinc-binding domain

    7. NM_028139.5 → NP_082415.2  ataxin-7-like protein 1 isoform 2

      See identical proteins and their annotated locations for NP_082415.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) shares no exons with variant 1. The encoded protein (isoform 2) thus shares no sequence with isoform 1. This variant is transcribed from the 5' end of the locus.
      Source sequence(s)
      AC132312, AC132354, AK013145
      Consensus CDS
      CCDS25874.2
      UniProtKB/Swiss-Prot
      Q8VD60, Q9CZ05
      Related
      ENSMUSP00000106448.3, ENSMUST00000110824.9

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      33196967..33426407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515129.5 → XP_006515192.1  ataxin-7-like protein 1 isoform X6

      UniProtKB/TrEMBL
      F6X2K7
      Conserved Domains (1) summary
      pfam08313
      Location:274 → 340
      SCA7; zinc-binding domain

    2. XM_006515130.5 → XP_006515193.1  ataxin-7-like protein 1 isoform X7

      UniProtKB/TrEMBL
      F6X2K7
      Related
      ENSMUSP00000118777.3, ENSMUST00000125192.9
      Conserved Domains (1) summary
      pfam08313
      Location:274 → 340
      SCA7; zinc-binding domain

    3. XM_006515124.5 → XP_006515187.1  ataxin-7-like protein 1 isoform X1

      UniProtKB/TrEMBL
      F7C0E4
      Related
      ENSMUSP00000122156.3, ENSMUST00000146040.9
      Conserved Domains (1) summary
      pfam08313
      Location:274 → 340
      SCA7; zinc-binding domain

    4. XM_036157509.1 → XP_036013402.1  ataxin-7-like protein 1 isoform X9

      UniProtKB/TrEMBL
      F6X2K7
      Conserved Domains (1) summary
      pfam08313
      Location:257 → 317
      SCA7; zinc-binding domain

    5. XM_006515125.5 → XP_006515188.1  ataxin-7-like protein 1 isoform X2

      UniProtKB/TrEMBL
      F7C0E4
      Conserved Domains (1) summary
      pfam08313
      Location:274 → 340
      SCA7; zinc-binding domain

    6. XM_006515128.5 → XP_006515191.1  ataxin-7-like protein 1 isoform X4

      UniProtKB/TrEMBL
      F6X2K7
      Conserved Domains (1) summary
      pfam08313
      Location:274 → 340
      SCA7; zinc-binding domain

    7. XM_006515126.5 → XP_006515189.1  ataxin-7-like protein 1 isoform X3

      UniProtKB/TrEMBL
      F7C0E4
      Conserved Domains (1) summary
      pfam08313
      Location:251 → 317
      SCA7; zinc-binding domain

    8. XM_006515134.5 → XP_006515197.1  ataxin-7-like protein 1 isoform X8

      See identical proteins and their annotated locations for XP_006515197.1

      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:150 → 216
      SCA7; zinc-binding domain

    9. XM_006515133.2 → XP_006515196.1  ataxin-7-like protein 1 isoform X8

      See identical proteins and their annotated locations for XP_006515196.1

      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:150 → 216
      SCA7; zinc-binding domain

    10. XM_036157510.1 → XP_036013403.1  ataxin-7-like protein 1 isoform X15

      UniProtKB/TrEMBL
      Q3TYJ2

    11. XM_006515132.5 → XP_006515195.1  ataxin-7-like protein 1 isoform X8

      See identical proteins and their annotated locations for XP_006515195.1

      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:150 → 216
      SCA7; zinc-binding domain

    12. XM_030246802.2 → XP_030102662.1  ataxin-7-like protein 1 isoform X12

      UniProtKB/TrEMBL
      B2RW07, Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:150 → 216
      SCA7; zinc-binding domain

    13. XM_017315123.3 → XP_017170612.1  ataxin-7-like protein 1 isoform X5

      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:165 → 231
      SCA7; zinc-binding domain

    14. XM_011243881.4 → XP_011242183.1  ataxin-7-like protein 1 isoform X13

      See identical proteins and their annotated locations for XP_011242183.1

      UniProtKB/TrEMBL
      D3Z7I2
      Conserved Domains (1) summary
      pfam08313
      Location:150 → 216
      SCA7; zinc-binding domain

    15. XM_030246803.1 → XP_030102663.1  ataxin-7-like protein 1 isoform X14

      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:58 → 124
      SCA7; zinc-binding domain

    16. XM_006515136.3 → XP_006515199.1  ataxin-7-like protein 1 isoform X11

      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:58 → 124
      SCA7; zinc-binding domain

    17. XM_017315124.3 → XP_017170613.1  ataxin-7-like protein 1 isoform X10

      UniProtKB/TrEMBL
      Q3U1F1
      Conserved Domains (1) summary
      pfam08313
      Location:91 → 157
      SCA7; zinc-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CZ05.2 GenPept UniProtKB/Swiss-Prot:Q9CZ05

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