Palmd palmdelphin [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Palmdprovided by MGI
Official Full Name: palmdelphinprovided by MGI
Primary source: MGI:MGI:2148896
See related: Ensembl:ENSMUSG00000033377 AllianceGenome:MGI:2148896
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: PALML; 4631423C22Rik
Summary: Predicted to be involved in regulation of cell shape. Located in cytoplasm. Is expressed in several structures, including brain; eye; myotome; nasal cavity; and tongue muscle. Orthologous to human PALMD (palmdelphin). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in subcutaneous fat pad adult (RPKM 10.9), genital fat pad adult (RPKM 8.6) and 19 other tissues See more
Orthologs: human all
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Genomic context

Location:: 3 G1; 3 50.49 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (116711911..116762896, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (116918262..116968952, complement)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium.
Title: Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium.
the results presented here demonstrate that cytosolic protein Palmd can promote myoblast differentiation, and is required for optimal muscle regeneration after CTX injection.
Title: Palmdelphin promotes myoblast differentiation and muscle regeneration.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2) 1 citation
Endonuclease-mediated (4)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH126151 (e-PCR)
- UniSTS:162863

Palmd (e-PCR), detects polymorphism
- UniSTS:525930

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of cell shape	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info	PubMed
located_in dendrite	ISO Inferred from Sequence Orthology more info
located_in dendritic spine	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: palmdelphin

Names: paralemmin-related

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.