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    Ccdc68 coiled-coil domain containing 68 [ Mus musculus (house mouse) ]

    Gene ID: 381175, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ccdc68provided by MGI
    Official Full Name
    coiled-coil domain containing 68provided by MGI
    Primary source
    MGI:MGI:3612676
    See related
    Ensembl:ENSMUSG00000038903 AllianceGenome:MGI:3612676
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in intracellular signal transduction; microtubule anchoring at centrosome; and protein localization. Predicted to be located in centriole. Predicted to be part of centriolar subdistal appendage. Orthologous to human CCDC68 (coiled-coil domain containing 68). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in placenta adult (RPKM 9.7), bladder adult (RPKM 2.2) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    18 E2; 18 43.78 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (70057929..70102559)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (69924858..69969488)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31564 Neighboring gene STARR-seq mESC enhancer starr_44954 Neighboring gene predicted gene, 36175 Neighboring gene STARR-seq mESC enhancer starr_44955 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene RAB27B, member RAS oncogene family Neighboring gene STARR-seq mESC enhancer starr_44957 Neighboring gene predicted gene, 41770 Neighboring gene STARR-seq mESC enhancer starr_44958 Neighboring gene dynactin associated protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC54896

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule anchoring at centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein localization ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of centriolar subdistal appendage ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in intracellular anatomical structure IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 68

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201362.2 → NP_958750.1  coiled-coil domain-containing protein 68

      See identical proteins and their annotated locations for NP_958750.1

      Status: PROVISIONAL

      Source sequence(s)
      AK078964
      Consensus CDS
      CCDS29330.1
      UniProtKB/Swiss-Prot
      Q80VD6, Q8BVC4
      Related
      ENSMUSP00000046197.5, ENSMUST00000043929.11
      Conserved Domains (1) summary
      COG1196
      Location:68 → 294
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      70057929..70102559
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526070.3 → XP_006526133.1  coiled-coil domain-containing protein 68 isoform X1

      Conserved Domains (1) summary
      COG1196
      Location:144 → 396
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_006526071.3 → XP_006526134.1  coiled-coil domain-containing protein 68 isoform X2

      Conserved Domains (1) summary
      COG1196
      Location:144 → 370
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    3. XM_006526076.3 → XP_006526139.1  coiled-coil domain-containing protein 68 isoform X4

      See identical proteins and their annotated locations for XP_006526139.1

      Conserved Domains (1) summary
      COG1196
      Location:68 → 320
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    4. XM_017317935.1 → XP_017173424.1  coiled-coil domain-containing protein 68 isoform X3

      Conserved Domains (1) summary
      COG1196
      Location:73 → 325
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    5. XM_006526075.3 → XP_006526138.1  coiled-coil domain-containing protein 68 isoform X4

      See identical proteins and their annotated locations for XP_006526138.1

      Conserved Domains (1) summary
      COG1196
      Location:68 → 320
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    6. XM_006526074.3 → XP_006526137.1  coiled-coil domain-containing protein 68 isoform X4

      See identical proteins and their annotated locations for XP_006526137.1

      Conserved Domains (1) summary
      COG1196
      Location:68 → 320
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    7. XM_011246971.3 → XP_011245273.1  coiled-coil domain-containing protein 68 isoform X4

      See identical proteins and their annotated locations for XP_011245273.1

      Conserved Domains (1) summary
      COG1196
      Location:68 → 320
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BVC4.1 GenPept UniProtKB/Swiss-Prot:Q8BVC4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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